Evidence map›Paper›PMID 38345724›Full record

ArticleJapanese journal of radiology2024

Combined visual and quantitative assessment of somatostatin receptor scintigraphy for staging and restaging of neuroendocrine tumors.

Yuya Ueki, Hideki Otsuka, Tamaki Otani, Ryosuke Kasai, Yoichi Otomi, Daiki Ikemitsu, Shota Azane, Yamato Kunikane, Takanori Bando, Noritake Matsuda and 3 more

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Article in Japanese journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Quantitative evaluation ofScientific reports · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Yuya UekiTokushima University Graduate School of Health Sciences, Tokushima, Japan.
Hideki OtsukaDepartment of Medical Imaging/Nuclear Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan. hideki.otsuka@tokushima-u.ac.jp.ORCID http://orcid.org/0000-0001-7165-6099
Tamaki OtaniAdvance Radiation Research, Education and Management Center, Tokushima University, Tokushima, Japan.
Ryosuke KasaiDepartment of Medical Imaging/Nuclear Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Yoichi OtomiDepartment of Radiology and Radiation Oncology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Daiki IkemitsuDepartment of Radiology, Tokushima University Hospital, Tokushima, Japan.
Shota AzaneDepartment of Radiology, Tokushima University Hospital, Tokushima, Japan.
Yamato KunikaneDepartment of Radiology, Tokushima University Hospital, Tokushima, Japan.
Takanori BandoDepartment of Radiology, Tokushima University Hospital, Tokushima, Japan.
Noritake MatsudaDepartment of Radiology, Tokushima University Hospital, Tokushima, Japan.
Yasuyuki OkadaDepartment of Gastroenterology and Oncology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Tetsuji TakayamaDepartment of Gastroenterology and Oncology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Masafumi HaradaDepartment of Radiology and Radiation Oncology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Tokushima University · JPTokushima University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSomatostatin receptor scintigraphy (SRS) using MATERIALS AND

methodsThis study included 21 patients with NETs who underwent

resultsSixty-three NEN lesions were evaluated. The mean ± standard deviation maximum SUVs (SUVmax) were liver: 4 h, 2.6 ± 1.0; 24 h, 2.2 ± 1.0; kidney: 4 h, 8.9 ± 1.8; 24 h, 7.0 ± 2.0; and spleen; 4 h, 11.3 ± 4.5; 24 h, 11.5 ± 7.6. Higher SUVmax was significantly associated with higher visual scores on dual-phase SPECT (4 h, p < 0.001; 24 h, p < 0.001) (4 h: scores 3 and 4, p < 0.05; scores 3 and 5: p < 0.01; scores 4 and 5: p < 0.01; 24 h: scores 3 and 4, p = 0.0748; scores 3 and 5: p < 0.01; scores 4 and 5: p < 0.01).

conclusionWe adapted the SUV to SRS and established the range of SUV for physiological uptake in the liver, kidney, and spleen. Combined visual and quantitative assessment is useful for imaging individual lesions in greater detail, and may serve as a new tumor marker of SRS for staging and restaging of NETs.

Indexed as

Neoplasm StagingNeuroendocrine TumorsRadiopharmaceuticalsReceptors, SomatostatinAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesSomatostatinTomography, Emission-Computed, Single-PhotonpentetreotideRadiopharmaceuticalsReceptors, SomatostatinSomatostatin111In-pentetreotideBecquerel calibration factor (BCF)Neuroendocrine tumors (NETs)Somatostatin receptor scintigraphy (SRS)Somatostatin receptor (SSTR)Standardized uptake value (SUV)

Identifiers

PMID38345724
OpenAlexW4391749905

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.