ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2024
Challenges and pitfalls during CRT implantation in patients with persistent left superior vena cava.
Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 4 citations in OpenAlex.
- Pacemaker Implantation in Persistent Left-Sided Superior Vena Cava: Challenges and Strategies.JACC. Case reports · 2026Article
- Thoracoscopic right atrial access for septal lead implantation: a novel minimally invasive technique (case report).European heart journal. Case reports · 2026Article
- Right-sided Cardiac Resynchronization Therapy via Left Bundle Branch Area Pacing in a Patient with Persistent Left Superior Vena Cava.The Journal of innovations in cardiac rhythm management · 2025Article
- Feasibility of anchoring active fixation quadripolar lead to the main body of the dilated coronary sinus in a patient with persistent left superior vena cava: a case report.European heart journal. Case reports · 2025Article
- Article
- How to achieve optimal cardiac resynchronization therapy implantation in individuals with persistent left superior vena cava.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Article
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPersistent left superior vena cava (PLSVC) is a rare venous anomaly, affecting 0.3-0.5% of the general population. Cardiac resynchronization therapy (CRT) implantation in patients with PLSVC is challenging due to a complex anatomy. Moreover, data on CRT implantation in this patient population is scarce. Our aim was to report a series of patients with PLSVC and CRT implantation focusing on challenges and pitfalls.
methodsElectronic medical databases on patients with CRT implantation at the University Heart Centers in Zurich, Switzerland, and Lübeck, Germany, were screened for individuals with a PLSVC. Clinical and demographic characteristics as well as procedural data were reported in all patients.
resultsThis study presents six cases with a median age of 66 years. CRT implantation was successful in five patients, leading to a reduced QRS duration and improved left ventricular ejection fraction. Atrial fibrillation, ischemic cardiomyopathy, valvular heart disease, and dilated cardiomyopathy were observed in this group as underlying conditions. Specialized tools, such as active fixation left ventricular leads, were utilized. One patient experienced major complications.
conclusionsThis case series shows that although challenging, conventional endovascular CRT implantation is feasible in PLSVC patients. Specialized tools for visualization and fixation may help. Our experiences highlight the importance of preprocedural evaluation of the anatomy and precise intervention planning.
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