Evidence map›Paper›PMID 38345357›Full record

ArticleEpilepsia open2024

Comparative effectiveness of digital mental healthcare models for adults with epilepsy: A study protocol of a randomized controlled trial.

Milena Gandy, Honor Coleman, Henry Cutler, Michael P Jones, Eyal Karin, Patrick Kwan, Armin Nikpour, Kaitlyn Parratt, Genevieve Rayner, Nickolai Titov and 5 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Epilepsia open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Milena GandySchool of Psychological Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0003-2161-3298
Honor ColemanMelbourne School of Psychological Sciences, The University of Melbourne, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-5532-9327
Henry CutlerAustralian Institute of Health Innovation, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-6015-092X
Michael P JonesSchool of Psychological Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0003-0565-4938
Eyal KarinSchool of Psychological Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-6152-9704
Patrick KwanDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0001-7310-276X
Armin NikpourDepartment of Neurology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Kaitlyn ParrattDepartment of Neurology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Genevieve RaynerMelbourne School of Psychological Sciences, The University of Melbourne, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-0747-3877
Nickolai TitovSchool of Psychological Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-7268-729X
Lisa ToddEpilepsy Action Australia, Sydney, New South Wales, Australia.
Elizabeth SeilAustralian Institute of Health Innovation, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0001-8438-6649
Toby Winton-BrownComprehensive Epilepsy Program, Alfred Hospital, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0001-8940-7816
Wendy WuSchool of Psychological Sciences, Macquarie University, Sydney, New South Wales, Australia.
Blake F DearSchool of Psychological Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0001-9324-3092
Macquarie University · AURoyal Prince Alfred Hospital · AUThe University of Melbourne · AUEpilepsy Action · GBMonash University · AUThe Alfred Hospital · AU

Funding

National Health and Medical Research Council MRFF 2022157
6 · The paper itself

Abstract

objectiveMental health complaints are prevalent among people with epilepsy, yet there are major barriers that prevent access to psychological care, including high out-of-pocket costs and a lack of accessible specialized services. The purpose of the current study is to examine the comparative efficacy, acceptability, cost-effectiveness, and long-term outcomes of a digital psychological intervention when delivered under two models of care (i.e., guided vs. unguided) in supporting the mental health and functioning of adults with epilepsy.

methodApproximately 375 participants across Australia will be enrolled. Eligible participants will have a confirmed diagnosis of epilepsy, experience difficulties with their emotional health, be at least 18 years of age, and live in Australia. Participants will be randomized (2:2:1) to receive the Wellbeing Neuro Course, a 10-week internet-delivered program, with (i.e., guided) or without guidance by a mental health clinician (i.e., unguided), or be allocated to a treatment-as-usual waiting-list control group. Participants will complete online questionnaires at pre-, post-treatment, and 3- and 12-month follow-up and consent to have their data linked to their medical records to capture healthcare system resource use and costs. ANALYSIS: Primary outcome measures will be symptoms of depression and anxiety. A cost-utility analysis will be undertaken using the Australian healthcare system perspective and according to current economic evaluation guidelines. Resource use and costs to the healthcare system during the study period will be captured via data linkage to relevant administrative datasets in Australia. SIGNIFICANCE: The results of this trial will provide important data concerning the relative outcomes of these different models of care and will inform the integration of digital psychological interventions translation into healthcare services. ETHICS AND DISSEMINATION: The Human Research Ethics Committee of Macquarie University approved the proposed study (Reference No: 520231325151475). The results will be disseminated through peer-reviewed publication(s). ANZCTR TRIAL REGISTRATION NUMBER: ACTRN12623001327673. PLAIN LANGUAGE SUMMARY: This study seeks to find out if a 10-week online psychological treatment can improve the mental health and well-being of Australian adults with epilepsy. Around 375 participants will be randomly assigned to different groups: one will receive treatment with guidance from mental health clinician (guided group), one without guidance (unguided group), and one starting later (waiting control group). All participants will fill out the same outcome measures online. The main goal of this research is to compare these groups and assess how well the treatment works in improving mental health outcomes.

Indexed as

Cognitive Behavioral TherapyEpilepsyMental Health ServicesAdultAustraliaDelivery of Health CareHumansRandomized Controlled Trials as Topicanxietycognitive behavior therapydepressionmoodonline

Identifiers

PMID38345357
PMCPMC10984311
OpenAlexW4391745702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.