← GLP-1 receptor agonists × cardiovascular events

TrialCirculation2024

Cardiovascular Outcomes in GRADE (Glycemia Reduction Approaches in Type 2 Diabetes: A Comparative Effectiveness Study).

Jennifer B Green et al.PubMed ↗Full text ↗Publisher ↗

The primary results report of NCT01794143.

What the trial testedas reported · 5,047 people · 2024

Not counted

Reduced cardiovascular events

−30%−46% to −9%

Bigger than 7 in 10 for cardiovascular events

As reported

HR 0.70, 95% CI 0.54–0.91

One number in the abstract

the abstract, start to end

… risk of MACE-5 (adjusted hazard ratio, 0.70 [95% CI, 0.54-0.91]; …

← favours treatmentfavours comparator →
could be chance
Cardiovascular events
HR 0.700.54–0.91
GLP-1 receptor agonistsOther glucose-loweringCardiovascular events
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16 papers cite it

2024
2025
2026
this paperpooled ittrialcites it

The trial

Full record →Abstract, authors, funding and every citing paper · PMID 38344820