Nortriptyline-Induced Room Tilt Illusion.

Bernard A Sarmiento, Rojan Varghese, Richa Vijayvargia, Matthew Gunther, Adam Fusick, Shixie Jiang

Open access · diamondAbstract readCase Reports

In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 100% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bernard A SarmientoCollege of Medicine, University of Central Florida, Orlando, USA.

Rojan VargheseDepartment of Psychiatry and Behavioral Neurosciences, Tampa General Hospital, University of South Florida, Tampa, USA.

Richa VijayvargiaDepartment of Psychiatry, University of Florida College of Medicine, Gainesville, USA.

Matthew GuntherDepartment of Psychiatry, Stanford University School of Medicine, Palo Alto, USA.

Adam FusickMental Health and Behavioral Services, James A Haley VA (Veteran Affairs), Tampa, USA.

Shixie JiangDepartment of Psychiatry, University of Florida College of Medicine, Gainesville, USA.

University of Central Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Room tilt illusion (RTI) is a rare and transient perceptual disturbance in which an individual perceives their surroundings as having been rotated or tilted, usually at 90 or 180 degrees. Primarily linked with vestibular disorders and neurological lesions, this report details the only reported occurrence of the RTI phenomena in nortriptyline use for treatment-refractory depression. The patient developed RTI six days after starting the medication and the disturbance resolved after medication cessation. Although the mechanism behind such a phenomenon with medication use has not been elucidated, its etiology may rest on the effect of tricyclic antidepressants on the vestibulo-thalamo-cortical system and visual-vestibular integration. Clinicians should be aware of the potential for such a medication-induced perceptual disturbance, especially in the workup for more serious etiologies in elderly patients with co-morbidities.

Indexed as

adverse drug effectmajor depressive disordermajor depressive disorder with psychotic featuresnortriptylineroom tilt illusiontricyclic anti-depressantsverticalityvisual tilt

Identifiers

PMID38344625

DOI10.7759/cureus.52101

PMCPMC10858726

OpenAlexW4390739450

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.