ArticleCureus2024
The Synthesis, Characterization, and Assessment of Antibacterial Properties of an Orthodontic Adhesive Containing Cerium-Substituted Hydroxyapatite Nanoparticles: An In Vitro Study.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Metal-Substituted Hydroxyapatite Nanoparticles as Antimicrobial and Osteogenic Biomaterials for Hard-Tissue Applications.Materials (Basel, Switzerland) · 2026Review
- Current applications and future perspectives on rare-earth-based materials in stomatology.iScience · 2025Review
- Article
- Iron and Magnesium Co-substituted Hydroxyapatite Nanoparticles in Orthodontic Composite: A Preliminary Assessment.Cureus · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction White spot lesions (WSLs) are early enamel caries lesions often seen in individuals receiving fixed orthodontic treatment. These lesions occur due to the buildup of plaque and the colonization of bacteria. WSL formation can be prevented by adequate oral hygiene measures and by the incorporation of antimicrobial nanoparticles (NPs) in orthodontic appliances and bonding systems. The aim of this research was to synthesize cerium-substituted hydroxyapatite nanoparticles (Ce-HAp NPs), characterize them, and assess their antimicrobial activity. Materials and methods This in vitro investigation involved the preparation of Ce-HAp NPs using the co-precipitation method, followed by their characterization using scanning electron microscope (SEM), energy-dispersive X-ray (EDAX), and Fourier transform infrared (FTIR). The NPs were prepared and subsequently added to an orthodontic adhesive. Antibacterial testing was conducted using the disc diffusion method against common oral pathogens (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.