Evidence map›Paper›PMID 38344394›Full record

ArticleJournal of affective disorders reports2023

Cortisol Regulation among Women Who Experience Suicidal Ideation during Pregnancy.

Shaimaa M Elrefaay, Sandra J Weiss

Open access · goldAbstract read
In one paragraph

Article in Journal of affective disorders reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. The NNDC Road Map for Depression Care and Focused Areas of Research.Focus (American Psychiatric Publishing) · 2025
    Article
  2. Targeted Research and Treatment Implications in Women With Depression.Focus (American Psychiatric Publishing) · 2025
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shaimaa M ElrefaayDepartment of Community Health Systems, University of California, San Francisco, 94143, USA.
Sandra J WeissDepartment of Community Health Systems, University of California, San Francisco, 94143, USA.
University of California, San Francisco · US

Funding

Antenatal Corticosteroids, Maternal Depression and Preterm Infant Stress ResponseR01HD081188 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WEISS, SANDRA JEAN · 2015 to 2019
$2.9M
NICHD NIH HHS R01 HD081188
6 · The paper itself

Abstract

Background: Suicidal thoughts occur in up to one third of pregnant women. Suicidal ideation (SI) has been linked to hypothalamic-pituitary-adrenal (HPA) axis dysregulation in other populations and could underlie SI during pregnancy when the HPA axis undergoes gestational transformation. However, no studies have evaluated the HPA axis in prenatal suicide risk, including regulation of cortisol. We examined whether SI is associated with distinct features of cortisol regulation among women during the 3 Methods: Sixty-four women completed measures of SI and provided 8 saliva samples across 2 consecutive days for cortisol assay. Three cortisol metrics were assessed in separate linear regression models (awakening response, diurnal slope, and area under the curve), along with selected covariates. Results: Women with SI ( Limitations: The small number of women with SI may have reduced the power to detect significant effects. Conclusions: Findings for women with SI differ from the expected pattern of cortisol secretion across the day and indicate circadian rhythm dysfunction. Further research can build on these results to clarify mechanisms underlying perinatal suicidality, with improved assessment and intervention targets as the goal.

Indexed as

cortisoldepressionHPA axispregnancySuicidal ideation

Identifiers

PMID38344394
PMCPMC10857818
OpenAlexW4385605503

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.