Evidence map›Paper›PMID 38343839›Full record

ArticleResearch square2024

Identifying and modulating neural signatures of stress susceptibility and resilience enables control of anhedonia.

Frances Xia, Valeria Fascianelli, Nina Vishwakarma, Frances Grace Ghinger, Stefano Fusi, Mazen A Kheirbek

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Frances XiaDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, USA.ORCID 0000-0001-7415-6620
Valeria FascianelliCenter for Theoretical Neuroscience, Columbia University, NY, USA.
Nina VishwakarmaNeuroscience Graduate Program, University of California, San Francisco, San Francisco, USA.
Frances Grace GhingerDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, USA.
Stefano FusiCenter for Theoretical Neuroscience, Columbia University, NY, USA.ORCID 0000-0002-3035-6652
Mazen A KheirbekDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, USA.ORCID 0000-0001-9157-7363
University of California, San Francisco · USCenter for Theoretical Biological Physics · USColumbia University Irving Medical Center · US

Funding

Hippocampal modulation of subcortical circuits in the control of emotional behaviorR01MH108623 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mazen A Kheirbek · 2016 to 2026
$6.0M
Cell-type, circuit and network mechanisms of adult oligodendrogenesis in memory storage and retrievalR01MH125515 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAN, JONAH R, KHEIRBEK, MAZEN A · 2021 to 2025
$3.4M
Circuit dynamics supporting associative learning in the dentate gyrusR01DC019813 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KHEIRBEK, MAZEN A · 2021 to 2025
$2.8M
How is anxiety-related information relayed across hippocampal-prefrontal circuitsR01MH117961 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KHEIRBEK, MAZEN A, SOHAL, VIKAAS SINGH · 2019 to 2022
$2.3M
Circuit and cellular mechanisms of adult neurogenesis in context encoding and discriminationR01MH111754 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KHEIRBEK, MAZEN A · 2017 to 2021
$2.0M
NIDCD NIH HHS R01 DC019813NIMH NIH HHS R01 MH108623NIMH NIH HHS R01 MH111754NIMH NIH HHS R01 MH117961NIMH NIH HHS R01 MH125515
6 · The paper itself

Abstract

Anhedonia is a core aspect of major depressive disorder. Traditionally viewed as a blunted emotional state in which individuals are unable to experience joy, anhedonia also diminishes the drive to seek rewards and the ability to value and learn about them

Identifiers

PMID38343839
PMCPMC10854313
OpenAlexW4391151492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.