Evidence map›Paper›PMID 38343811›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis: Rationale and design for a randomized, placebo-controlled, double-blind, 2 × 2 trial of administration of prebiotics and cholecalciferol (vitamin D

Alisa K Sivapiromrat, Pichatorn Suppakitjanusant, Yanling Wang, Jose Binongo, William R Hunt, Andrew Gewirtz, Jessica A Alvarez, Chengcheng Hu, Samuel Weinstein, Ishaan Jathal and 2 more

Open access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Alisa K SivapiromratEmory University, Atlanta, GA, USA.ORCID 0009-0009-7531-6740
Pichatorn SuppakitjanusantEmory University, Atlanta, GA, USA.
Yanling WangCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
Jose BinongoEmory University, Atlanta, GA, USA.
William R HuntEmory University, Atlanta, GA, USA.
Andrew GewirtzCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
Jessica A AlvarezEmory University, Atlanta, GA, USA.
Chengcheng HuEmory University, Atlanta, GA, USA.
Samuel WeinsteinEmory University, Atlanta, GA, USA.
Ishaan JathalEmory University, Atlanta, GA, USA.
Thomas R ZieglerEmory University, Atlanta, GA, USA.
Vin TangprichaEmory University, Atlanta, GA, USA.
Emory University · USGeorgia State University · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Pilot & Feasibility CoreP30DK125013 · NIDDK · EMORY UNIVERSITY · PI NAEL A MCCARTY · 2020 to 2026
$6.7M
NCATS NIH HHS UL1 TR002378NIDDK NIH HHS P30 DK125013
6 · The paper itself

Abstract

Individuals with cystic fibrosis (CF) have dysfunctional intestinal microbiota and increased gastrointestinal (GI) inflammation also known as GI dysbiosis. It is hypothesized that administration of high-dose cholecalciferol (vitamin D

Identifiers

PMID38343811
PMCPMC10854319
OpenAlexW4390786834

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.