Evidence map›Paper›PMID 38343805›Full record

ArticleResearch square2024

Pre-Pulse Inhibition of an escape response in adult fruit fly,

Erika Viragh, Lenke Asztalos, Michaela Fenckova, Tamas Szlanka, Zoltan Gyorgypal, Karoly Kovacs, Joanna IntHout, Pavel Cizek, Mihaly Konda, Emanuela Szucs and 8 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 7 countries.

Erika ViraghInstitute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.
Lenke AsztalosAktogen Hungary Ltd., Szeged, Hungary.
Michaela FenckovaDepartment of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.
Tamas SzlankaInstitute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.
Zoltan GyorgypalInstitute of Biophysics & Core Facilities, HUN-REN Biological Research Centre, Szeged, Hungary.
Karoly KovacsInstitute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.
Joanna IntHoutDepartment for Health Evidence (HEV), Radboud University Medical Center, Nijmegen, The Netherlands.
Pavel CizekDepartment of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.
Mihaly KondaAktogen Hungary Ltd., Szeged, Hungary.
Emanuela SzucsAktogen Hungary Ltd., Szeged, Hungary.
Agnes ZvaraLaboratory of Functional Genomics, HUN-REN Biological Research Centre Szeged, Hungary.
Judit BiroAktogen Hungary Ltd., Szeged, Hungary.
Eniko CsapoAktogen Hungary Ltd., Szeged, Hungary.
Tamas LukacsovichUniversity of Zurich, Brain Research Institute, Zurich, Switzerland.
Zoltan HegedusInstitute of Biophysics & Core Facilities, HUN-REN Biological Research Centre, Szeged, Hungary.
Laszlo PuskasLaboratory of Functional Genomics, HUN-REN Biological Research Centre Szeged, Hungary.
Annette SchenckDepartment of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.
Zoltan AsztalosInstitute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.
HUN-REN Szegedi Biológiai Kutatóközpont · HURadboud University Nijmegen · NLImmunoGenes (Hungary) · HUUniversity of Cambridge · GBUniversity of Zurich · CH

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
NIGMS NIH HHS R01 GM084947NIH HHS P40 OD018537
6 · The paper itself

Abstract

Pre-Pulse Inhibition (PPI) is a neural process where suppression of a startle response is elicited by preceding the startling stimulus (Pulse) with a weak, non-startling one (Pre-Pulse). Defective PPI is widely employed as a behavioural endophenotype in humans and mammalian disorder-relevant models for neuropsychiatric disorders. We have developed a user-friendly, semi-automated, high-throughput-compatible

Indexed as

3Rsbehaviour systemDrosophilaDysbindinNmdar1Pre-Pulse Inhibition

Identifiers

PMID38343805
PMCPMC10854311
OpenAlexW4391132225

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.