Preoperative maltodextrin in minimally invasive colorectal surgery: Is it safe for diabetics? A randomised controlled trial.

Background and Aims: Preoperative fasting can result in thirst and fatigue. We evaluated the blood glucose levels during and after surgery following the administration of maltodextrin among patients including diabetics, undergoing minimally invasive colorectal surgery. Methods: One hundred and fifty patients undergoing colorectal surgery were randomised into group CL (received 50 g of 12.5% maltodextrin dissolved in 400 ml of water 2 h before surgery) and group W (received 400 ml of plain water 2 h before surgery). Blood glucose was checked at T0 (induction of anaesthesia), T2 (2 h), T4 (4 h), T6 (6 h) of surgery and eight hourly postoperatively in the intensive care unit (ICU) for 24 h. Thirst or discomfort before induction, gastric aspirate after intubation, incidence of hyperglycaemia and need for insulin intervention intra- and postoperatively were also assessed. Results: Mean (standard deviation [SD]) blood glucose levels were lower at T2 in group CL (136.2 [28.4] mg/dl) than in group W (157.8 [37.8] mg/dl) ( Conclusion: Preoperative administration of oral maltodextrin lowers the blood glucose levels from 2 h into surgery until 24 h postoperatively, even among controlled diabetic patients, and improves preoperative thirst scores in patients undergoing minimally invasive colorectal surgery.