ArticleRenal failure2024
The relationship of platelet distribution width with all-cause and cardiovascular mortality in peritoneal dialysis patients.
Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Platelet indices and incident CKD in high-risk individuals.Clinical and experimental nephrology · 2026Article
- The SII-PNI score: A novel composite biomarker for personalized mortality risk prediction in peritoneal dialysis patients.PloS one · 2025Article
- Article
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Authors and funding
5 authors.
Funding
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Abstract
backgroundCardiovascular disease (CVD) is a major complication in peritoneal dialysis (PD) patients. Previous studies have demonstrated that platelet distribution width (PDW) is associated with cardiovascular events in hemodialysis (HD) patients. In this study, we hypothesized that elevated PDW can predict all-cause and cardiovascular mortality in PD patients.
methodsWe recruited PD patients for a single-center retrospective cohort study from 1 January 2007, to 30 June 2020. Receiver-operating characteristic (ROC) curves were made to determine the PDW cutoff value for predicting all-cause mortality. The propensity score matching (PSM) method was used to improve the equilibrium between groups. The relation of PDW with all-cause and cardiovascular mortality was analyzed by Cox proportional hazards models. Restricted cubic spline (RCS) models were used to determine whether there was a linear relationship between PDW and all-cause and cardiovascular mortality.
resultsA total of 720 PD patients were screened, and 426 PD patients were enrolled after PSM. After adjusting for confounders, Cox proportional hazards models showed that the PDW value was positively correlated with the risk of all-cause and cardiovascular mortality (HR = 1.162, 95% CI 1.057-1.278,
conclusionElevated PDW is independently associated with all-cause and cardiovascular mortality in PD patients.
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