ArticleJournal of imaging informatics in medicine2024
PET KinetiX-A Software Solution for PET Parametric Imaging at the Whole Field of View Level.
Article in Journal of imaging informatics in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Parametric imaging of dynamic long-axial-field-of-view PET scans: Technical challenges, statistical insights and clinical applications.Zeitschrift fur medizinische Physik · 2026Review
- Automated long axial field of view PET image processing and kinetic modelling with the TurBO toolbox.European journal of nuclear medicine and molecular imaging · 2026Article
- Article
- LAFOV PET as an enabling platform for pharmacokinetics-informed digital twins.Frontiers in medicine · 2026Article
- Regional impact of time-to-equilibrium on indirect Patlak whole-body parametric imaging: a multi-tissue class analysis at the entire body level.EJNMMI physics · 2025Article
- Fast 4D-PET parametric imaging computation at the whole field of view level: Reliability under simulated conditions of PET KinetiX, a dedicated software solution.European journal of nuclear medicine and molecular imaging · 2025Article
- Article
- Impact of different parametric Patlak imaging approaches and comparison with a 2-tissue compartment pharmacokinetic model with a long axial field-of-view (LAFOV) PET/CT in oncological patients.European journal of nuclear medicine and molecular imaging · 2025Article
- A Methodology to Measure Glucose Metabolism by Quantitative Analysis of PET Images.Journal of healthcare informatics research · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Kinetic modeling represents the ultimate foundations of PET quantitative imaging, a unique opportunity to better characterize the diseases or prevent the reduction of drugs development. Primarily designed for research, parametric imaging based on PET kinetic modeling may become a reality in future clinical practice, enhanced by the technical abilities of the latest generation of commercially available PET systems. In the era of precision medicine, such paradigm shift should be promoted, regardless of the PET system. In order to anticipate and stimulate this emerging clinical paradigm shift, we developed a constructor-independent software package, called PET KinetiX, allowing a faster and easier computation of parametric images from any 4D PET DICOM series, at the whole field of view level. The PET KinetiX package is currently a plug-in for Osirix DICOM viewer. The package provides a suite of five PET kinetic models: Patlak, Logan, 1-tissue compartment model, 2-tissue compartment model, and first pass blood flow. After uploading the 4D-PET DICOM series into Osirix, the image processing requires very few steps: the choice of the kinetic model and the definition of an input function. After a 2-min process, the PET parametric and error maps of the chosen model are automatically estimated voxel-wise and written in DICOM format. The software benefits from the graphical user interface of Osirix, making it user-friendly. Compared to PMOD-PKIN (version 4.4) on twelve
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.