Evidence map›Paper›PMID 38342820›Full record

ArticlePsycho-oncology2024

A dyadic analysis of financial toxicity and health-related quality of life among bone marrow transplant patients and their caregivers.

Jean S Edward, Mary Kay Rayens, Laurie E McLouth, Lori P Eisele, Joan Scales, Lovoria B Williams, Gerhard Hildebrandt

Open access · hybridAbstract read
In one paragraph

Article in Psycho-oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
6.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jean S EdwardCollege of Nursing, University of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0001-9184-1048
Mary Kay RayensCollege of Nursing, University of Kentucky, Lexington, Kentucky, USA.
Laurie E McLouthDepartment of Behavioral Health, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0002-4888-6520
Lori P EiseleCollege of Nursing, University of Kentucky, Lexington, Kentucky, USA.
Joan ScalesPsycho-oncology Program, Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA.
Lovoria B WilliamsCollege of Nursing, University of Kentucky, Lexington, Kentucky, USA.
Gerhard HildebrandtEllis Fischel Cancer Center, Missouri University Health Care, Columbia, Missouri, USA.
University of Kentucky · USUniversity of Missouri Health System · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Jennifer F Rogers · 2013 to 2026
$38.3M
Institutional Career Development CoreKL2TR001996 · NCATS · UNIVERSITY OF KENTUCKY · PI BUSH, MATTHEW LEE, KELLY, THOMAS H. · 2016 to 2025
$7.1M
NCATS NIH HHS KL2 TR001996NCI NIH HHS P30 CA177558
6 · The paper itself

Abstract

objectiveRelatively few dyad-based studies have evaluated the shared psychosocial and financial toxicity (FT) experiences of hematologic patients and their caregivers, especially those undergoing bone marrow transplantations (BMTs). This study evaluated the association of FT with health-related quality of life (QOL) among BMT patient-caregiver dyads.

methodsSurvey and electronic health record data were collected between April 2021 and January 2022 from BMT patients and their caregivers pre- (T1) and post-intervention (T2). Thirty-four patient-caregiver dyads completed surveys; all dyads included a patient experiencing elevated T1 FT. The effect of the total FT score (i.e., the combination of psychological response, coping behaviors, and material conditions domain scores) on physical health, mental health, anxiety, depression and distress scores was evaluated using Actor-Partner Interdependence Modeling (APIM).

resultsPatients and caregivers who reported lower total FT scores had better physical and mental health, and lower anxiety, depressive symptoms, distress (APIM actor effects). None of the partner effects were significant in the APIM models. Other model findings indicated that compared with caregivers, patients had lower reported physical health; mental health scores were higher, on average, for all participants at the T2 compared with T1; and members of dyads whose caregiver took time off work reported better physical health and lower depressive symptoms and distress than those whose caregiver did not.

conclusionsOur study addresses a significant gap in dyad-based cancer FT studies; the findings underscore the need for additional research to help develop tailored dyad-level FT interventions for improving health-related QOL among BMT patients.

Indexed as

CaregiversQuality of LifeBone Marrow TransplantationCross-Sectional StudiesFinancial StressHumansbone marrow transplantationcancercaregiversfinancial toxicityhealth-related quality of lifeoncology

Identifiers

PMID38342820
PMCPMC10947586
OpenAlexW4391750915

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.