Evidence map›Paper›PMID 38342633›Full record

ArticleFEBS open bio2024

Alfaxalone does not have long-term effects on goldfish pyramidal neuron action potential properties or GABA

Domenic Di Stefano, Haushe Suganthan, Leslie Buck

Abstract read
In one paragraph

Article in FEBS open bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Domenic Di StefanoDepartment of Cell and Systems Biology, University of Toronto, Canada.ORCID 0009-0005-5307-3574
Haushe SuganthanDepartment of Cell and Systems Biology, University of Toronto, Canada.
Leslie BuckDepartment of Cell and Systems Biology, University of Toronto, Canada.

Funding

Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada 458021
6 · The paper itself

Abstract

Anesthetics have varying physiological effects, but most notably alter ion channel kinetics. Alfaxalone is a rapid induction and washout neuroactive anesthetic, which potentiates γ-aminobutyric acid (GABA)-activated GABA

Indexed as

AnestheticsPregnanedionesReceptors, GABA-AAction PotentialsAnimalsgamma-Aminobutyric AcidGoldfishHypoxiaPyramidal CellsalphaxaloneAnestheticsgamma-Aminobutyric AcidPregnanedionesReceptors, GABA-Aalfaxalonecommon goldfishGABAGABA‐A receptorpyramidal neurons

Identifiers

PMID38342633
PMCPMC10988724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.