Evidence map›Paper›PMID 38342031›Full record

ArticleSleep medicine2024

The effects of sustained mild sleep restriction on stress and distress among healthy adults: Findings from two randomized crossover studies.

Giada Benasi, Bin Cheng, Brooke Aggarwal, Marie-Pierre St-Onge

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Sleep medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02960776 (Effect of Long Term Sleep Restriction on Energy Balance), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02960776 nacompletednot on this map

Effect of Long Term Sleep Restriction on Energy Balance

TypeinterventionalSponsorColumbia UniversityRan2016 to 2023Enrolled45ConditionsSleep, Obesity, Sleep RestrictionArmsSleep Restriction (SR)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Giada BenasiDivision of General Medicine, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA. Electronic address: gb2710@cumc.columbia.edu.
Bin ChengDepartment of Biostatistics, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, USA.
Brooke AggarwalDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA; Center of Excellence for Sleep & Circadian Research, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Marie-Pierre St-OngeDivision of General Medicine, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA; Center of Excellence for Sleep & Circadian Research, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Columbia University Irving Medical Center · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Mechanisms addressing the causal relationships of sleep, circadian rhythms, and cardiometabolic healthR35HL155670 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARIE-PIERRE ST-ONGE · 2021 to 2026
$5.4M
OBESITY RESEARCH CENTER TRAINING PROGRAMT32DK007559 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI DYMPNA GALLAGHER · 1989 to 2026
$4.3M
Impact of circadian misalignment on energy balance regulationR01HL142648 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ST-ONGE, MARIE-PIERRE · 2018 to 2022
$3.8M
Effect of long-term sleep restriction on energy balanceR01HL128226 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ST-ONGE, MARIE-PIERRE · 2016 to 2019
$3.4M
Sleep stability, weight, and glycemic controlR01DK128154 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LAFERRERE, BLANDINE B, ST-ONGE, MARIE-PIERRE · 2021 to 2023
$972k
American Heart Association-American Stroke Association 811531NCATS NIH HHS UL1 TR001873NHLBI NIH HHS R01 HL128226NHLBI NIH HHS R01 HL142648NHLBI NIH HHS R35 HL155670NIDDK NIH HHS R01 DK128154NIDDK NIH HHS T32 DK007559
6 · The paper itself

Abstract

OBJECTIVE/

backgroundExperimental studies suggest that sleep loss affects psychological outcomes. However, most studies focus on acute severe in-laboratory sleep restriction, with limited ecological validity. This study examines the impact of sustained mild sleep restriction (SR) on stress and distress among healthy adults in a naturalistic home environment. PATIENTS/

methodsWe analyzed data from two randomized crossover studies. Individuals who regularly slept 7-9 h/night completed two 6-wk intervention phases separated by a 6-wk washout: habitual sleep (HS: maintenance of habitual bed and wake times) and SR (delayed bedtime by 1.5 h/night and maintenance of habitual wake time). Adherence to sleep duration requirements was verified with wrist actigraphy and daily sleep diaries during each intervention phase. Measures of perceived stress, subjective anxiety, subjective depression, rumination, and cortisol were collected at baseline and endpoint of each intervention phase.

resultsSixty-two participants (age 36.4 ± 14.0 y, 85.5 % women, 63.3 % racial/ethnic minority) were included in our analyses. Mean total sleep time was 7.4 ± 0.4 h/night during HS and 6.2 ± 0.4 h/night during SR (p < 0.001). Higher perceived stress (3.6 ± 1.0, p = 0.0007) and subjective anxiety (1.1 ± 0.5, p = 0.039) were observed after SR compared to HS. No effect of sleep condition was observed on subjective depression, rumination, and cortisol.

conclusionsOur findings suggest that prolonged mildly insufficient sleep, similar to what commonly experienced in the real world, can lead to increased perceived stress and subjective anxiety in healthy adults. Addressing sleep loss, even if mild, should be a key component of interventions aimed at promoting mental health in the general population.

Indexed as

EthnicitySleep Initiation and Maintenance DisordersAdultCross-Over StudiesFemaleHumansHydrocortisoneMaleMiddle AgedMinority GroupsRandomized Controlled Trials as TopicSleepYoung AdultHydrocortisoneAnxietyCortisolDepressionRuminationSleep restrictionStress

Identifiers

PMID38342031
PMCPMC10932935
OpenAlexW4391487219

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.