Evidence map›Paper›PMID 38341800›Full record

Trial reportJournal of the American Medical Informatics Association : JAMIA2024

Artificial intelligence predictive analytics in heart failure: results of the pilot phase of a pragmatic randomized clinical trial.

Konstantinos Sideris, Charlene R Weir, Carsten Schmalfuss, Heather Hanson, Matt Pipke, Po-He Tseng, Neil Lewis, Karim Sallam, Biykem Bozkurt, Thomas Hanff and 9 more

Registry-linked trialOpen access · hybridAbstract readPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Medical Informatics Association : JAMIA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04502563 (Continuous Wearable Monitoring Analytics to Improve Outcomes in Heart Failure - LINK-HF2 Multicenter Implementation Study), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04502563 nacompletednot on this map

Continuous Wearable Monitoring Analytics to Improve Outcomes in Heart Failure - LINK-HF2 Multicenter Implementation Study

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2021 to 2024Enrolled176ConditionsHeart FailureArmsRemote monitoring and predictive analytics, Sham comparator
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 1 country.

Konstantinos SiderisCardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, United States.ORCID 0009-0007-9369-0782
Charlene R WeirCardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, United States.ORCID 0000-0002-8297-2860
Carsten SchmalfussCardiology Section, Medical Service, Malcom Randall VA Medical Center, Gainesville, FL 32608, United States.
Heather HansonCardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, United States.
Matt PipkePhysIQ, Inc., Chicago, IL 60563, United States.
Po-He TsengPhysIQ, Inc., Chicago, IL 60563, United States.
Neil LewisCardiology Section, Medical Service, Hunter Holmes McGuire Veterans Medical Center, Richmond, VA 23249, United States.
Karim SallamCardiology Section, Medical Service, VA Palo Alto Health Care System, Palo Alto, CA 94304, United States.
Biykem BozkurtCardiology Section, Medical Service, Michael E. DeBakey VA Medical Center, Houston, TX 77030, United States.ORCID 0000-0002-6362-0253
Thomas HanffCardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, United States.
Richard SchofieldCardiology Section, Medical Service, Malcom Randall VA Medical Center, Gainesville, FL 32608, United States.
Karen LarimerPhysIQ, Inc., Chicago, IL 60563, United States.
Christos P KyriakopoulosCardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, United States.ORCID 0000-0001-9415-1245
Iosif TalebCardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, United States.
Lina BrinkerCardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, United States.
Tempa CurryCardiology Section, Medical Service, Malcom Randall VA Medical Center, Gainesville, FL 32608, United States.
Cheri KnechtCardiology Section, Medical Service, Malcom Randall VA Medical Center, Gainesville, FL 32608, United States.
Jorie M ButlerCardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, United States.ORCID 0000-0003-4519-7997
Josef StehlikCardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, United States.ORCID 0000-0002-7362-0513
University of Utah · USUniversity of Florida · USMichael E. DeBakey VA Medical Center · USVA Palo Alto Health Care System · USVirginia Commonwealth University · US

Funding

CTSA UM1 Program at University of UtahUM1TR004409 · NCATS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI RACHEL HESS, Jennifer Juhl Majersik · 2023 to 2026
$21.9M
Continuous Wearable Monitoring Analytics to Improve Outcomes in Heart Failure - LINK-HF2 multicenter implementation studyI01HX002922 · VA · VA SALT LAKE CITY HEALTHCARE SYSTEM · PI STEHLIK, JOSEF · 2020 to 2025
–
HSRD VA I01 HX002922NCATS NIH HHS UM1 TR004409
6 · The paper itself

Abstract

objectivesWe conducted an implementation planning process during the pilot phase of a pragmatic trial, which tests an intervention guided by artificial intelligence (AI) analytics sourced from noninvasive monitoring data in heart failure patients (LINK-HF2). MATERIALS AND

methodsA mixed-method analysis was conducted at 2 pilot sites. Interviews were conducted with 12 of 27 enrolled patients and with 13 participating clinicians. iPARIHS constructs were used for interview construction to identify workflow, communication patterns, and clinician's beliefs. Interviews were transcribed and analyzed using inductive coding protocols to identify key themes. Behavioral response data from the AI-generated notifications were collected.

resultsClinicians responded to notifications within 24 hours in 95% of instances, with 26.7% resulting in clinical action. Four implementation themes emerged: (1) High anticipatory expectations for reliable patient communications, reduced patient burden, and less proactive provider monitoring. (2) The AI notifications required a differential and tailored balance of trust and action advice related to role. (3) Clinic experience with other home-based programs influenced utilization. (4) Responding to notifications involved significant effort, including electronic health record (EHR) review, patient contact, and consultation with other clinicians. DISCUSSION: Clinician's use of AI data is a function of beliefs regarding the trustworthiness and usefulness of the data, the degree of autonomy in professional roles, and the cognitive effort involved.

conclusionThe implementation planning analysis guided development of strategies that addressed communication technology, patient education, and EHR integration to reduce clinician and patient burden in the subsequent main randomized phase of the trial. Our results provide important insights into the unique implications of implementing AI analytics into clinical workflow.

Indexed as

Artificial IntelligenceHeart FailureAmbulatory Care FacilitiesCommunicationHumansInformation Technologyartificial intelligencecomputerized decision supportheart failurehome monitoringimplementation

Identifiers

PMID38341800
PMCPMC10990545
OpenAlexW4392730338

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.