Evidence map›Paper›PMID 38341660›Full record

ArticleBioinformatics (Oxford, England)2024

NFTest: automated testing of Nextflow pipelines.

Yash Patel, Chenghao Zhu, Takafumi N Yamaguchi, Yuan Zhe Bugh, Mao Tian, Aaron Holmes, Sorel T Fitz-Gibbon, Paul C Boutros

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Comprehensive analysis of the gastric metatranscriptome reveals specific viral signatures associated with gastric cancer.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Identification of non-canonical peptides with moPepGen.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. PipeVal: light-weight extensible tool for file validation.Bioinformatics (Oxford, England) · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yash PatelJonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, United States.ORCID 0000-0003-3113-7010
Chenghao ZhuJonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, United States.
Takafumi N YamaguchiJonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, United States.ORCID 0000-0003-1082-3871
Yuan Zhe BughJonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, United States.
Mao TianJonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, United States.
Aaron HolmesJonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, United States.ORCID 0000-0002-1012-7879
Sorel T Fitz-GibbonJonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, United States.
Paul C BoutrosJonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, United States.ORCID 0000-0003-0553-7520

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
Tool Core- BoutrosU54HG012517 · NHGRI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WATSON, KAROL E · 2022 to 2025
$10.6M
Advancing method benchmarking and data sharing through crowd-sourced competitions in cancer researchU24CA248265 · NCI · SAGE BIONETWORKS · PI BOUTROS, PAUL CHRISTOPHER, VARMA, SUSHEEL · 2020 to 2024
$4.1M
The Evolution of Sarcoma Drug Sensitivity through Time and SpaceR01CA244729 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BOUTROS, PAUL CHRISTOPHER, SORAGNI, ALICE · 2020 to 2024
$3.4M
Virginia-UCLA-Toronto Biomarker Characterization CenterU2CCA271894 · NCI · OLD DOMINION UNIVERSITY · PI OLIVER John SEMMES · 2022 to 2026
$3.2M
Germline Determinants of Prostate Cancer EvolutionR01CA270108 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PAUL T. SPELLMAN · 2023 to 2026
$2.9M
NCI NIH HHS P30 CA016042NCI NIH HHS R01 CA244729NCI NIH HHS R01 CA270108NCI NIH HHS U24 CA248265NCI NIH HHS U2C CA271894NHGRI NIH HHS U54 HG012517NIH HHS P30CA016042
6 · The paper itself

Abstract

motivationThe ongoing expansion in the volume of biomedical data has contributed to a growing complexity in the tools and technologies used in research with an increased reliance on complex workflows written in orchestration languages such as Nextflow to integrate algorithms into processing pipelines. The growing use of workflows involving various tools and algorithms has led to increased scrutiny of software development practices to avoid errors in individual tools and in the connections between them.

resultsTo facilitate test-driven development of Nextflow pipelines, we created NFTest, a framework for automated pipeline testing and validation with customizability options for Nextflow features. It is open-source, easy to initialize and use, and customizable to allow for testing of complex workflows with test success configurable through a broad range of assertions. NFTest simplifies the testing burden on developers by automating tests once defined and providing a flexible interface for running tests to validate workflows. This reduces the barrier to rigorous biomedical workflow testing and paves the way toward reducing computational errors in biomedicine. AVAILABILITY AND IMPLEMENTATION: NFTest is an open-source Python framework under the GPLv2 license and is freely available at https://github.com/uclahs-cds/tool-NFTest. The call-sSNV Nextflow pipeline is available at: https://github.com/uclahs-cds/pipeline-call-sSNV.

Indexed as

Computational BiologySoftwareAlgorithmsLanguageWorkflow

Identifiers

PMID38341660
PMCPMC10881102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.