Evidence map›Paper›PMID 38341416›Full record

ArticleNature communications2024

A hepatic network of dendritic cells mediates CD4 T cell help outside lymphoid organs.

Kieran English, Rain Kwan, Lauren E Holz, Claire McGuffog, Jelte M M Krol, Daryan Kempe, Tsuneyasu Kaisho, William R Heath, Leszek Lisowski, Maté Biro and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. CD4Nature immunology · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 5 countries.

Kieran EnglishCentenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.ORCID 0000-0001-7224-9153
Rain KwanCentenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Lauren E HolzDepartment of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.ORCID 0000-0003-4897-0981
Claire McGuffogCentenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Jelte M M KrolCentenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.ORCID 0000-0002-3943-7707
Daryan KempeEMBL Australia, Single Molecule Science node, School of Biomedical Sciences, University of New South Wales, Sydney, NSW, Australia.
Tsuneyasu KaishoDepartment of Immunology, Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan.ORCID 0000-0003-2616-1665
William R HeathDepartment of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.ORCID 0000-0001-9670-259X
Leszek LisowskiChildren's Medical Research Institute, Translational Vectorology Research Unit, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.ORCID 0000-0002-4772-8651
Maté BiroEMBL Australia, Single Molecule Science node, School of Biomedical Sciences, University of New South Wales, Sydney, NSW, Australia.ORCID 0000-0001-5852-3726
Geoffrey W McCaughanCentenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
David G Bowen *Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia. d.bowen@centenary.org.au.ORCID 0000-0002-7965-5581
Patrick Bertolino *Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia. p.bertolino@centenary.org.au.ORCID 0000-0001-8244-7057
Royal Prince Alfred Hospital · AUThe University of Melbourne · AUUNSW Sydney · AULeiden University · NLThe University of Sydney · AUWakayama Medical University · JP

Funding

Department of Health | National Health and Medical Research Council (NHMRC) APP1146677
6 · The paper itself

Abstract

While CD4

Indexed as

CD4-Positive T-LymphocytesLiverLymphoid TissueAntigensCD8-Positive T-LymphocytesDendritic CellsHumansAntigens

Identifiers

PMID38341416
PMCPMC10858872
OpenAlexW4391723591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.