Evidence map›Paper›PMID 38340972›Full record

ArticleRespiratory physiology & neurobiology2024

Pediatric patients diagnosed as overweight and obese have an elevated risk of dyspnea.

Lydia S Robson, Abidan Abulimiti, Jorge Z Granados, Ayesha N Zia, Bryce N Balmain, James A Pawelczyk, Tony G Babb

Abstract readMulticenter Study
In one paragraph

Article in Respiratory physiology & neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lydia S RobsonDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, USA.
Abidan AbulimitiInstitute for Exercise and Environmental Medicine, University of Texas Southwestern Medical Center and Texas Health Presbyterian Hospital Dallas, USA.
Jorge Z GranadosInstitute for Exercise and Environmental Medicine, University of Texas Southwestern Medical Center and Texas Health Presbyterian Hospital Dallas, USA.
Ayesha N ZiaDepartment of Pediatrics, University of Texas Southwestern Medical Center, USA.
Bryce N BalmainInstitute for Exercise and Environmental Medicine, University of Texas Southwestern Medical Center and Texas Health Presbyterian Hospital Dallas, USA.
James A PawelczykNoll Physiological Research Center, Department of Kinesiology, Penn State University, USA.
Tony G BabbInstitute for Exercise and Environmental Medicine, University of Texas Southwestern Medical Center and Texas Health Presbyterian Hospital Dallas, USA. Electronic address: drtonybabb@texashealth.org.

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI PHILIPP E SCHERER · 2022 to 2026
$7.4M
Respiratory Effects of Obesity in Children: Longitudinal Consequences after 6 Years of AgingR01HL136643 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI TONY G BABB · 2017 to 2026
$5.0M
University of Texas Southwestern - Stimulating Access to Research in Residency (UT-StARR) ProgramR38HL150214 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI Anand Kumar Rohatgi · 2021 to 2026
$1.8M
Targeting breathing limitations to improve functional outcomes in HFpEFK99HL164957 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI BALMAIN, BRYCE · 2023 to 2024
$270k
NCATS NIH HHS UL1 TR002014NHLBI NIH HHS K99 HL164957NHLBI NIH HHS R01 HL136643NHLBI NIH HHS R38 HL150214NIDDK NIH HHS P30 DK127984
6 · The paper itself

Abstract

We investigated whether pediatric patients with overweight and obesity are more likely to have dyspnea compared with those who are non-overweight. We collected de-identified data from TriNetX, a global federated multicenter research database, using both the UT Southwestern Medical Center and multinational Research Networks. Our analysis focused on patients aged 8-12 years. We identified overweight and obesity using ICD-10-CM codes E66 and dyspnea using code R06.0. Patients with overweight and obesity had a significantly higher risk of dyspnea compared with those who were non-overweight. This association was observed in both the UT Southwestern Network (risk ratio: 1.81, p < 0.001) and the Research Network (risk ratio: 2.70, p < 0.001). Furthermore, within the UT Southwestern Network, the risk was found to be higher in females compared with males (risk ratio: 2.17 vs. 1.67). These results have significant clinical implications, suggesting that clinicians should consider overweight and obesity as independent risk factors for dyspnea in pediatric patients after excluding other possible contributing factors.

Indexed as

ObesityOverweightBody Mass IndexChildDyspneaFemaleHumansMaleRisk FactorsChildrenDyspneaObesityOverweight

Identifiers

PMID38340972
PMCPMC10947832

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.