Evidence map›Paper›PMID 38340728›Full record

SynthesisCell reports. Medicine2024

Federated machine learning in healthcare: A systematic review on clinical applications and technical architecture.

Zhen Ling Teo, Liyuan Jin, Siqi Li, Di Miao, Xiaoman Zhang, Wei Yan Ng, Ting Fang Tan, Deborah Meixuan Lee, Kai Jie Chua, John Heng and 3 more

Erratum issuedAbstract readSystematic Review
In one paragraph

Synthesis in Cell reports. Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 95 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  8. Technical review of artificial intelligence in TCR-T therapy.Journal of the National Cancer Center · 2026
    Review
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Zhen Ling TeoSingapore National Eye Centre, Singapore, Singapore; Singapore Eye Research Institute, Singapore, Singapore.
Liyuan JinSingapore Eye Research Institute, Singapore, Singapore; Duke-NUS Medical School, Singapore, Singapore.
Siqi LiSingapore Eye Research Institute, Singapore, Singapore; Duke-NUS Medical School, Singapore, Singapore.
Di MiaoSingapore Eye Research Institute, Singapore, Singapore; Duke-NUS Medical School, Singapore, Singapore.
Xiaoman ZhangSingapore Eye Research Institute, Singapore, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Wei Yan NgSingapore National Eye Centre, Singapore, Singapore; Singapore Eye Research Institute, Singapore, Singapore.
Ting Fang TanSingapore National Eye Centre, Singapore, Singapore; Singapore Eye Research Institute, Singapore, Singapore.
Deborah Meixuan LeeSingapore Eye Research Institute, Singapore, Singapore; Institute of High Performance Computing, Agency for Science, Technology and Research, Singapore, Singapore.
Kai Jie ChuaSingapore National Eye Centre, Singapore, Singapore; Singapore Eye Research Institute, Singapore, Singapore.
John HengSingapore National Eye Centre, Singapore, Singapore; Singapore Eye Research Institute, Singapore, Singapore.
Yong LiuLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Rick Siow Mong GohLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Daniel Shu Wei TingSingapore National Eye Centre, Singapore, Singapore; Singapore Eye Research Institute, Singapore, Singapore; Duke-NUS Medical School, Singapore, Singapore. Electronic address: daniel.ting@duke-nus.edu.sg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Federated learning (FL) is a distributed machine learning framework that is gaining traction in view of increasing health data privacy protection needs. By conducting a systematic review of FL applications in healthcare, we identify relevant articles in scientific, engineering, and medical journals in English up to August 31st, 2023. Out of a total of 22,693 articles under review, 612 articles are included in the final analysis. The majority of articles are proof-of-concepts studies, and only 5.2% are studies with real-life application of FL. Radiology and internal medicine are the most common specialties involved in FL. FL is robust to a variety of machine learning models and data types, with neural networks and medical imaging being the most common, respectively. We highlight the need to address the barriers to clinical translation and to assess its real-world impact in this new digital data-driven healthcare scene.

Indexed as

Delivery of Health CareMachine LearningHumansNeural Networks, Computerartificial intelligencefederated learninghealthcaresystematic review

Identifiers

PMID38340728
PMCPMC10897620

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.