Evidence map›Paper›PMID 38340634›Full record

ArticleRedox biology2024

Essential role of ROS - 8-Nitro-cGMP signaling in long-term memory of motor learning and cerebellar synaptic plasticity.

Sho Kakizawa, Tomoko Arasaki, Ayano Yoshida, Ayami Sato, Yuka Takino, Akihito Ishigami, Takaaki Akaike, Shuichi Yanai, Shogo Endo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Redox biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Involvement of ROS signal in aging and regulation of brain functions.The journal of physiological sciences : JPS · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sho KakizawaDepartment of Biological Chemistry, Graduate School and Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan. Electronic address: kakizawa.sho.4u@kyoto-u.ac.jp.
Tomoko ArasakiAging Neuroscience Research Team, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan.
Ayano YoshidaAging Neuroscience Research Team, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan.
Ayami SatoMolecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan.
Yuka TakinoMolecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan.
Akihito IshigamiMolecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan.
Takaaki AkaikeDepartment of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.
Shuichi YanaiAging Neuroscience Research Team, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan.
Shogo EndoAging Neuroscience Research Team, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan. Electronic address: sendo@tmig.or.jp.
Tokyo Metropolitan Institute of Gerontology · JPKyoto University · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although reactive oxygen species (ROS) are known to have harmful effects in organisms, recent studies have demonstrated expression of ROS synthases at various parts of the organisms and the controlled ROS generation, suggesting possible involvement of ROS signaling in physiological events of individuals. However, physiological roles of ROS in the CNS, including functional roles in higher brain functions or neuronal activity-dependent ROS production, remain to be elucidated. Here, we demonstrated involvement of ROS - 8-NO

Indexed as

Neuronal PlasticityNitrogen DioxideCerebellumCyclic GMPHumansMemory, Long-TermReactive Oxygen Species8-nitroguanosine 3',5'-cyclic monophosphateCyclic GMPNitrogen DioxideReactive Oxygen SpeciesAntioxidantCerebellumMotor learningNitric oxideReactive oxygen speciesSynaptic plasticity

Identifiers

PMID38340634
PMCPMC10869263
OpenAlexW4391482150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.