ArticleEuropean geriatric medicine2024
Association between comorbidities associated with diabetes and higher-level functional status in older patients with type 2 diabetes mellitus: a cross sectional study.
Article in European geriatric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The prevalence and associations of stroke history with self-reported sleep disturbances in China: a nationwide cross-sectional study.BMC public health · 2026Article
- Predicting the risk of activities of daily living dysfunction in middle-aged and older adults with comorbid hypertension and diabetes: a national population-based survey analysis.BMC medical informatics and decision making · 2026Article
- A Comparison of Higher-Level Functional Capacity Between Older Adults with and Without Type 2 Diabetes Mellitus: A Cross-Sectional Study Using Propensity Score Matching.Geriatrics (Basel, Switzerland) · 2025Article
- Ethnicity predicts long-term depressive symptom patterns in older adults with type 2 diabetes.International psychogeriatrics · 2025Article
- Characteristic Changes of Prefrontal and Motor Areas in Patients with Type 2 Diabetes and Major Depressive Disorder During a Motor Task of Tai Chi Chuan: A Functional Near-Infrared Spectroscopy Study.Brain and behavior · 2024Article
- Aging trajectories of subscales in higher-level functional capacity among community-dwelling older Japanese adults: the Otassha study.Aging clinical and experimental research · 2024Article
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Authors and funding
10 authors.
Funding
Abstract
purposeTo investigate the association between comorbidities associated with diabetes and higher-level functional status as well as the relationship between comorbidities associated with diabetes and higher-level functional status in older patients with type 2 diabetes mellitus who have better social networks.
methodsParticipants were outpatients with type 2 diabetes aged ≥ 65 years, excluding individuals with severe cardiovascular or respiratory illness, hyperglycaemic crisis, type 1 diabetes, or diabetic foot. The Tokyo Metropolitan Institute of Gerontology Index of Competence (TMIG-IC) was used to evaluate the higher-level functional status. A TMIG-IC score of ≤ 9, instrumental activities of daily living (IADL) ≤ 4, intellectual activity or social role ≤ 3 were defined as decline in higher-level functional status. The comorbidities investigated included peripheral neuropathy, retinopathy, nephropathy, cognitive impairment, depression, frailty, sarcopenia, low muscle strength, stroke, heart disease, and arthritis.
resultsThe analysis included 198 patients (mean age 75.9 ± 5.7 years, male 60.1%). After adjusting for potential confounders, depression was associated with TMIG-IC (Prevalence ratio (PR) 2.34, 95% confidence interval (CI) 1.44-3.82), low muscle strength was associated with IADL (PR 2.85, 95% CI 1.30-6.27), and frailty was associated with intellectual activity (PR 1.38, 95% CI 1.10-1.74). In the model with social networks added as a confounder, the relationship between depression or low muscle strength and higher-level functional status was not statistically significant.
conclusionComorbidities of depression and low muscle strength for older patients with type 2 diabetes mellitus increase the risk of malfunctioning of higher-level functional status. Increased interactions with family, friends and neighbours may reduce this event.
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