Evidence map›Paper›PMID 38340278›Full record

ArticleJournal of autism and developmental disorders2025

Social Anhedonia Accounts for Greater Variance in Internalizing Symptoms than Autism Symptoms in Autistic and Non-Autistic Youth.

Alan H Gerber, Jason W Griffin, Cara M Keifer, Matthew D Lerner, James C McPartland

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Article in Journal of autism and developmental disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alan H GerberChild Study Center, Yale School of Medicine, New Haven, CT, CT 06519, USA.ORCID http://orcid.org/0000-0002-8133-3995
Jason W GriffinChild Study Center, Yale School of Medicine, New Haven, CT, CT 06519, USA.
Cara M KeiferChild Study Center, Yale School of Medicine, New Haven, CT, CT 06519, USA.
Matthew D LernerDepartment of Psychology, Stony Brook University, Stony Brook, NY, USA.
James C McPartlandChild Study Center, Yale School of Medicine, New Haven, CT, CT 06519, USA.
Yale University · USStony Brook University · US

Funding

Optimizing Prediction of Social Deficits in Autism Spectrum DisordersR01MH110585 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI LERNER, MATTHEW DANIEL · 2016 to 2020
$2.2M
Multimodel Assessment of Social Process Systems across Neurodevelopmental DisordersR01MH107426 · NIMH · YALE UNIVERSITY · PI MCPARTLAND, JAMES CHARLES, SRIHARI, VINOD H. · 2015 to 2017
$651k
NIMH NIH HHS 1R01MH107426-01NIMH NIH HHS 1R01MH110585-01NIMH NIH HHS MH18268
6 · The paper itself

Abstract

purposeSocial anhedonia is a transdiagnostic trait that reflects reduced pleasure from social interaction. It has historically been associated with autism, however, very few studies have directly examined behavioral symptoms of social anhedonia in autistic youth. We investigated rates of social anhedonia in autistic compared to non-autistic youth and the relative contributions of autism and social anhedonia symptoms to co-occurring mental health.

methodsParticipants were 290 youth (M

resultsAutistic youth were more likely to meet criteria for social anhedonia than non-autistic youth. There was a significant positive relationship between age and social anhedonia symptom severity, but there was no association between sex and social anhedonia. Dominance analysis revealed that social anhedonia symptom severity had the strongest association with symptoms of depression and social anxiety, while symptoms of ADHD, generalized anxiety, and separation anxiety were most strongly associated with autism symptom severity.

conclusionThis was the first study to tease out the relative importance of social anhedonia and autism symptoms in understanding psychiatric symptoms in autistic youth. Findings revealed higher rates of social anhedonia in autistic youth. Our results indicate that social anhedonia is an important transdiagnostic trait that plays a unique role in understanding co-occurring depression and social anxiety in autistic youth. Future research should utilize longitudinal data to test the transactional relationships between social anhedonia and internalizing symptoms over time.

Indexed as

AnhedoniaAutism Spectrum DisorderAutistic DisorderDepressionSocial BehaviorAdolescentAnxietyChildFemaleHumansMaleSeverity of Illness IndexAutism Spectrum DisordersDepressionSocial AnhedoniaSocial AnxietyYouth

Identifiers

PMID38340278
OpenAlexW4391723279

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.