Evidence map›Paper›PMID 38339600›Full record

ArticleSensors (Basel, Switzerland)2024

Exploring Novel Sensor Design Ideas through Concentration-Induced Conformational Changes in PEG Single Chains.

Miao Yu, Chong Jiang, Bing Lai, Kai Zhang

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Miao YuSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, China.ORCID 0000-0002-0493-7277
Chong JiangSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Bing LaiSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Kai ZhangSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, China.

Funding

National Natural Science Foundation of China 22303057Sichuan Province Science Technology Support Program 2022YFG0068University-Local City Science and Technology Cooperation Program 2022CDZG-11
6 · The paper itself

Abstract

Polyethylene glycol (PEG) is an artificial polymer with good biocompatibility and a low cost, which has a wide range of applications. In this study, the dynamic response of PEG single chains to different ion concentrations was investigated from a microscopic point of view based on single-molecule force spectroscopy, revealing unique interactions that go beyond the traditional sensor-design paradigm. Under low concentrations of potassium chloride, PEG single chains exhibit a gradual reduction in rigidity, while, conversely, high concentrations induce a progressive increase in rigidity. This dichotomy serves as the cornerstone for a profound understanding of PEG conformational dynamics under diverse ion environments. Capitalizing on the remarkable sensitivity of PEG single chains to ion concentration shifts, we introduce innovative sensor-design ideas. Rooted in the adaptive nature of PEG single chains, these sensor designs extend beyond the traditional applications, promising advancements in environmental monitoring, healthcare, and materials science.

Indexed as

ion concentrationPEGsingle-chain rigiditysingle-molecule force spectroscopy

Identifiers

PMID38339600
PMCPMC10856974

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.