Evidence map›Paper›PMID 38339404›Full record

ArticleCancers2024

Lymphedema and Trismus after Head and Neck Cancer, and the Impact on Body Image and Quality of Life.

Coralie R Arends, Lisette van der Molen, Josephine E Lindhout, Karoline Bragante, Arash Navran, Michiel W M van den Brekel, Martijn M Stuiver

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Beyond feasibility: the case for lymphoedema-stratified rehabilitation trials in head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Article
  4. Observational
  5. Article
  6. Body Image Distress and Depression in Head and Neck Cancer Patients- a Narrative Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  7. The impact of lymphedema severity on shoulder joint function and muscle activation patterns in breast cancer survivors: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Coralie R ArendsDepartment of Head and Neck Oncology and Surgery, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0003-3750-6657
Lisette van der MolenDepartment of Head and Neck Oncology and Surgery, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-0514-2142
Josephine E LindhoutDepartment of Head and Neck Oncology and Surgery, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-6470-4344
Karoline BraganteDepartment of Physical Rehabilitation, Federal University of Health Science of Porto Alegre, Porto Alegre 90050-170, Brazil.ORCID 0000-0002-3023-134X
Arash NavranDepartment of Radiation Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0001-7006-7807
Michiel W M van den BrekelDepartment of Head and Neck Oncology and Surgery, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-6338-6743
Martijn M StuiverDepartment of Head and Neck Oncology and Surgery, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-7794-7767
The Netherlands Cancer Institute · NLUniversidade Federal de Ciências da Saúde de Porto Alegre · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the prevalence of chronic lymphedema and trismus in patients > 6 months after head and neck cancer (HNC) treatment, and to explore how the severity of these conditions correlates with body image and quality of life.

methodsThe cross-sectional sample included 59 patients, treated for HNC between six months to three years ago. Physical measurements were performed to assess the presence of external lymphedema and trismus (<36 mm). Furthermore, participants completed two questionnaires regarding body image (BIS) and quality of life (UW-QoL V4).

resultsLymphedema prevalence was 94.1% (95% CI 0.86-0.98), with a median severity score of 9 (range 0-24). Trismus prevalence in this sample was 1.2%. The median BIS score was 2, indicating a positive body image. The UW-QoL score showed a good QOL with a median of 100. Only the domain of saliva and overall related health had a lower median of 70 and 60, respectively. There was no correlation between lymphedema and body image (r = 0.08,

conclusionLymphedema is a highly prevalent, but moderately severe late side-effect of HNC with a limited impact on quality of life domains except for speech, in our cohort.

Indexed as

body imagehead and neck cancerlymphedemaquality of lifetrismus

Identifiers

PMID38339404
PMCPMC10854984
OpenAlexW4391566883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.