Evidence map›Paper›PMID 38339388›Full record

ArticleCancers2024

Intraoral Ultrasound versus MRI for Depth of Invasion Measurement in Oral Tongue Squamous Cell Carcinoma: A Prospective Diagnostic Accuracy Study.

Mikkel Kaltoft, Christoffer Holst Hahn, Marcus Wessman, Martin Lundsgaard Hansen, Tina Klitmøller Agander, Fatemeh Makouei, Irene Wessel, Tobias Todsen

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mikkel KaltoftDepartment of Oto-Rhino-Laryngology, Head- and Neck Surgery and Audiology Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0009-0000-1900-3445
Christoffer Holst HahnDepartment of Oto-Rhino-Laryngology, Head- and Neck Surgery and Audiology Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Marcus WessmanDepartment of Oto-Rhino-Laryngology, Head- and Neck Surgery and Audiology Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Martin Lundsgaard HansenDepartment of Radiology, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Tina Klitmøller AganderDepartment of Pathology, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0009-0007-8792-9275
Fatemeh MakoueiDepartment of Oto-Rhino-Laryngology, Head- and Neck Surgery and Audiology Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0002-6443-7362
Irene WesselDepartment of Oto-Rhino-Laryngology, Head- and Neck Surgery and Audiology Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Tobias TodsenDepartment of Oto-Rhino-Laryngology, Head- and Neck Surgery and Audiology Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0003-3267-3560
Copenhagen University Hospital · DKUniversity of Copenhagen · DK

Funding

Novo Nordisk Foundation NNF21SA0069151
6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) of the tongue is the most common type of oral cavity cancer, and tumor depth of invasion (DOI) is an important prognostic factor. In this study, we investigated the accuracy of intraoral ultrasound and magnetic resonance imaging (MRI) for assessing DOI in patients with OSCC. Histopathological measurement of DOI was used as a reference standard. We conducted a prospective study including patients planned for surgical treatment of OSCC in the tongue. The DOI was measured in an outpatient setting by intraoral ultrasound and MRI, and was compared to the histopathological DOI measurements. Bland-Altman analysis compared the mean difference and 95% limits of agreement (LOA) for ultrasound and MRI, and the Wilcoxon signed-rank test was used to test for significance. The correlation was evaluated using Pearson's correlation coefficient. We included 30 patients: 26 with T1 or T2 tumors, and 4 with T3 tumors. The mean difference from histopathology DOI was significantly lower for ultrasound compared to MRI (0.95 mm [95% LOA -4.15 mm to 6.06 mm] vs. 1.90 mm [95% LOA -9.02 mm and 12.81 mm],

Indexed as

depth of invasionintraoral ultrasoundMRIoral cancerpathologystagingtongue cancer

Identifiers

PMID38339388
PMCPMC10854529
OpenAlexW4391432092

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.