Evidence map›Paper›PMID 38339385›Full record

ArticleCancers2024

High Numbers of CD163+ Tumor-Associated Macrophages Predict Poor Prognosis in HER2+ Breast Cancer.

Minna M Jääskeläinen, Ritva Tumelius, Kirsi Hämäläinen, Kirsi Rilla, Sanna Oikari, Aino Rönkä, Tuomas Selander, Arto Mannermaa, Satu Tiainen, Päivi Auvinen

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Minna M JääskeläinenCancer Center, Kuopio University Hospital, Wellbeing Services County of North Savo, 70029 Kuopio, Finland.
Ritva TumeliusKuopio Center for Gene and Cell Therapy, 70210 Kuopio, Finland.ORCID 0009-0009-4867-8869
Kirsi HämäläinenInstitute of Clinical Medicine, Clinical Pathology and Forensic Medicine, University of Eastern Finland, 70211 Kuopio, Finland.
Kirsi RillaInstitute of Biomedicine, University of Eastern Finland, 70211 Kuopio, Finland.ORCID 0000-0002-7862-5727
Sanna OikariInstitute of Biomedicine, University of Eastern Finland, 70211 Kuopio, Finland.
Aino RönkäCancer Center, Kuopio University Hospital, Wellbeing Services County of North Savo, 70029 Kuopio, Finland.ORCID 0000-0001-6007-3648
Tuomas SelanderScience Services Center, Kuopio University Hospital, Wellbeing Services County of North Savo, 70029 Kuopio, Finland.
Arto MannermaaInstitute of Clinical Medicine, Clinical Pathology and Forensic Medicine, University of Eastern Finland, 70211 Kuopio, Finland.
Satu TiainenCancer Center, Kuopio University Hospital, Wellbeing Services County of North Savo, 70029 Kuopio, Finland.
Päivi AuvinenCancer Center, Kuopio University Hospital, Wellbeing Services County of North Savo, 70029 Kuopio, Finland.
University of Eastern Finland · FIKuopio University Hospital · FI

Funding

Finnish Society for Oncology
6 · The paper itself

Abstract

Tumor-associated macrophages (TAMs) are associated with a poor outcome in breast cancer (BC), but their prognostic value in different BC subtypes has remained somewhat unclear. Here, we investigated the prognostic value of M2-like TAMs (CD163+) and all TAMs (CD68+) in a patient cohort of 278 non-metastatic BC patients, half of whom were HER2+ (

Indexed as

breast cancerCD163CD68HER2trastuzumabtumor-associated macrophage

Identifiers

PMID38339385
PMCPMC10854814
OpenAlexW4391431989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.