Evidence map›Paper›PMID 38339363›Full record

ReviewCancers2024

Emerging Therapies in Management of Cholangiocarcinoma.

Jessica Speckart, Veronica Rasmusen, Zohray Talib, Dev A GnanaDev, Amir A Rahnemai-Azar

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. PTPN9 dephosphorylates IGF1RJournal of experimental & clinical cancer research : CR · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Splicing, Signaling, and Survival: The Role of RBM39 in Cholangiocarcinoma Progression.Cellular and molecular gastroenterology and hepatology · 2025
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jessica SpeckartSchool of Medicine, California University of Science and Medicine, Colton, CA 92324, USA.
Veronica RasmusenSchool of Medicine, California University of Science and Medicine, Colton, CA 92324, USA.
Zohray TalibDepartment of Medicine, Arrowhead Regional Medical Center, California University of Science and Medicine, Colton, CA 92324, USA.
Dev A GnanaDevDepartment of Surgery, Arrowhead Regional Medical Center, Colton, CA 92324, USA.
Amir A Rahnemai-AzarDivision of Surgical Oncology, Department of Surgery, Arrowhead Regional Cancer Center, California University of Science and Medicine, Colton, CA 92324, USA.
Arrowhead Regional Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholangiocarcinoma is a heterogeneous group of biliary tract cancers that has a poor prognosis and globally increasing incidence and mortality. While surgical resection remains the only curative option for the treatment of cholangiocarcinoma, the majority of cancers are unresectable at the time of diagnosis. Additionally, the prognosis of cholangiocarcinoma remains poor even with the current first-line systemic therapy regimens, highlighting the difficulty of treating locally advanced, metastatic, or unresectable cholangiocarcinoma. Through recent developments, targetable oncogenic driver mutations have been identified in the pathogenesis of cholangiocarcinoma, leading to the utilization of molecular targeted therapeutics. In this review, we comprehensively discuss the latest molecular therapeutics for the treatment of cholangiocarcinoma, including emerging immunotherapies, highlighting promising developments and strategies.

Indexed as

biliary tract cancercholangiocarcinomagenomic aberrationgenomicsimmunotherapymolecular targeted therapiesprecision medicinesystemic therapytargeted therapy

Identifiers

PMID38339363
PMCPMC10854763
OpenAlexW4391385225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.