Evidence map›Paper›PMID 38339342›Full record

ArticleCancers2024

miRNA-221 and miRNA-483-3p Dysregulation in Esophageal Adenocarcinoma.

Isotta Bozzarelli, Arianna Orsini, Federica Isidori, Luca Mastracci, Deborah Malvi, Marialuisa Lugaresi, Silvia Fittipaldi, Livia Gozzellino, Annalisa Astolfi, Jari Räsänen and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Biology · 2026
    Article
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 4 countries.

Isotta BozzarelliGastrointestinal Genetics Lab, CIC bioGUNE-BRTA, 48160 Derio, Spain.
Arianna OrsiniDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, via Massarenti 9, 40138 Bologna, Italy.
Federica IsidoriDipartimento di Genetica Medica, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, via Massarenti 9, 40138 Bologna, Italy.
Luca MastracciPathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, 16100 Genoa, Italy.ORCID 0000-0003-0193-5281
Deborah MalviDipartimento di Genetica Medica, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, via Massarenti 9, 40138 Bologna, Italy.ORCID 0000-0001-6109-3675
Marialuisa LugaresiDipartimento di Genetica Medica, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, via Massarenti 9, 40138 Bologna, Italy.ORCID 0000-0002-0965-9595
Silvia FittipaldiDipartimento di Genetica Medica, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, via Massarenti 9, 40138 Bologna, Italy.
Livia GozzellinoDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, via Massarenti 9, 40138 Bologna, Italy.
Annalisa AstolfiDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, via Massarenti 9, 40138 Bologna, Italy.ORCID 0000-0002-2732-0747
Jari RäsänenDepartment of Cardiothoracic Surgery, University of Helsinki and Helsinki University Hospital, 00100 Helsinki, Finland.ORCID 0000-0002-7826-532X
Antonia D'ErricoDipartimento di Genetica Medica, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, via Massarenti 9, 40138 Bologna, Italy.ORCID 0000-0003-2747-3732
Riccardo RosatiDepartment of Gastrointestinal Surgery, San Raffaele Hospital, Vita-Salute San Raffaele University, 20132 Milan, Italy.ORCID 0000-0002-2608-5749
Roberto FioccaPathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, 16100 Genoa, Italy.ORCID 0000-0002-8856-6185
Marco SeriDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, via Massarenti 9, 40138 Bologna, Italy.ORCID 0000-0003-2425-2176
Kausilia K KrishnadathLaboratory of Experimental Medicine and Pediatrics (LEMP), Department of Gastroenterology and Hepatology, University Hospital Antwerp, University of Antwerp, 2180 Antwerp, Belgium.
Elena BonoraDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, via Massarenti 9, 40138 Bologna, Italy.
Sandro MattioliDivision of Thoracic Surgery, Maria Cecilia Hospital, 48010 Cotignola, Italy.
Medica (Italy) · ITUniversity of Bologna · ITOspedale Policlinico San Martino · ITCIC bioGUNE · ESMaria Cecilia Hospital · ITUniversity of Antwerp · BEUniversity of Helsinki · FIVita-Salute San Raffaele University · IT

Funding

AIRC IG151791 to MS and RFO2020 to EB
6 · The paper itself

Abstract

Alterations in microRNA (miRNA) expression have been reported in different cancers. We assessed the expression of 754 oncology-related miRNAs in esophageal adenocarcinoma (EAC) samples and evaluated their correlations with clinical parameters. We found that miR-221 and 483-3p were consistently upregulated in EAC patients vs. controls (Wilcoxon signed-rank test: miR-221

Indexed as

esophageal adenocarcinomamicroRNAmiR–221miR–483–3p

Identifiers

PMID38339342
PMCPMC10854562
OpenAlexW4391348880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.