ReviewInternational journal of molecular sciences2024
The Changes in the Quantity of Lymphocyte Subpopulations during the Process of Sepsis.
Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prognostic value of the CALLY index in sepsis: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Identification and validation of MYC as an autophagy-related gene for diagnosis and immune infiltration in sepsis-induced myocardial dysfunction.Journal of cardiothoracic surgery · 2026Article
- Causal relationships between antibody-induced immune responses and sepsis: Evidence from genetic studies.Medicine · 2026Article
- Systemic immune-inflammation (SII) index as a novel prognostic biomarker in critically ill patients with sepsis: analysis of the MIMIC-IV cohort and predictive modeling based on machine learning.BMC infectious diseases · 2026Article
- Regulatory T Cells in Diabetic Wound Healing: A Comprehensive Review.Journal of inflammation research · 2026Review
- Association between prognostic nutritional index and 28-day mortality in patients with sepsis-associated acute respiratory distress syndrome.Frontiers in nutrition · 2026Article
- Establishing Reference Intervals for Adult Lymphocyte Subsets: Single-Platform Volume Analysis Reveals Age- and Sex-Specific Trajectories of Immunosenescence.Journal of immunology research · 2026Article
- Lymphocyte function inhibition and exhaustion in sepsis: mechanisms and applications.Frontiers in immunology · 2026Review
- A new type of biomarker for heat stress: insights from immunology.Frontiers in immunology · 2026Review
- Molecular analysis of immune cell subsets and cytokine profiles in septic Vietnamese patients.Clinical and experimental medicine · 2025Article
- A Quinoxaline Derivative as a New Therapeutic Agent for Sepsis through Suppression of TLR4 Signaling Pathways.Inflammation · 2025Article
- Protective Effects of a Dihydrodiazepine Against Endotoxin Shock Through Suppression of TLR4/NF-κB/IRF3 Signaling Pathways.Inflammation · 2025Article
- Article
- Impact of absolute lymphocyte count upon admission to ICU on 28-day mortality in sepsis patients in ICU.Frontiers in immunology · 2025Article
- Establishing the reference intervals for subpopulations of T lymphocytes, B lymphocytes, and natural killer cells: insight from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Article
- Prognostic nutritional index as a potential predictor of prognosis in patients with sepsis: a retrospective cohort study.Frontiers in nutrition · 2025Article
- Tim-3 pathway dysregulation and targeting in sepsis-induced immunosuppression.European journal of medical research · 2024Review
- Association between D-dimer to lymphocyte ratio and in hospital all-cause mortality in elderly patients with sepsis: a cohort of 1123 patients.Frontiers in cellular and infection microbiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sepsis remains a global challenge, especially in low- and middle-income countries, where there is an urgent need for easily accessible and cost-effective biomarkers to predict the occurrence and prognosis of sepsis. Lymphocyte counts are easy to measure clinically, and a large body of animal and clinical research has shown that lymphocyte counts are closely related to the incidence and prognosis of sepsis. This review extensively collected experimental articles related to lymphocyte counts since the unification of the definition of sepsis. The article categorizes and discusses the relationship between absolute lymphocyte counts, intrinsic lymphocyte subsets, effector T-lymphocytes, B-lymphocytes, dendritic cells, and the incidence and prognosis of sepsis. The results indicate that comparisons of absolute lymphocyte counts alone are meaningless. However, in addition to absolute lymphocyte counts, innate lymphocyte subsets, effector T-cells, B-lymphocytes, and dendritic cells have shown certain research value in related studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.