Evidence map›Paper›PMID 38339099›Full record

ArticleInternational journal of molecular sciences2024

Rapid Biodistribution of Fluorescent Outer-Membrane Vesicles from the Intestine to Distant Organs via the Blood in Mice.

Béatrice Schaack, Corinne Mercier, Maya Katby, Dalil Hannani, Julien Vollaire, Julie Suzanne Robert, Clément Caffaratti, Françoise Blanquet, Olivier Nicoud, Véronique Josserand and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Frontiers in bacterial outer membrane vesicles: From basic characteristics to cancer therapy.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2026
    Article
  6. Review
  7. Review
  8. Review
  9. Secretory phospholipase ACommunications biology · 2025
    Article
  10. Review
  11. International journal of molecular sciences · 2025
    Article
  12. EnterohemorrhagicFrontiers in cellular and infection microbiology · 2025
    Article
  13. Frontiers in immunology · 2025
    Article
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Béatrice SchaackCNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, University Grenoble Alpes, F-38000 Grenoble, France.ORCID 0000-0002-3008-7309
Corinne MercierCNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, University Grenoble Alpes, F-38000 Grenoble, France.ORCID 0000-0003-4118-1904
Maya KatbyCNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, University Grenoble Alpes, F-38000 Grenoble, France.
Dalil HannaniCNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, University Grenoble Alpes, F-38000 Grenoble, France.ORCID 0000-0001-5097-1401
Julien VollaireINSERM U1209, CNRS UMR5309, Institute for Advanced Biosciences, University Grenoble Alpes, F-38000 Grenoble, France.
Julie Suzanne RobertEtablissement Français du Sang, Département Scientifique Auvergne Rhône-Alpes, F-38000 Grenoble, France.
Clément CaffarattiCNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, University Grenoble Alpes, F-38000 Grenoble, France.
Françoise BlanquetCNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, University Grenoble Alpes, F-38000 Grenoble, France.ORCID 0000-0003-3887-0442
Olivier NicoudINSERM U1209, CNRS UMR5309, Institute for Advanced Biosciences, University Grenoble Alpes, F-38000 Grenoble, France.
Véronique JosserandINSERM U1209, CNRS UMR5309, Institute for Advanced Biosciences, University Grenoble Alpes, F-38000 Grenoble, France.ORCID 0000-0001-6733-3801
David LaurinINSERM U1209, CNRS UMR5309, Institute for Advanced Biosciences, University Grenoble Alpes, F-38000 Grenoble, France.ORCID 0000-0001-9339-8369

Funding

Agence Nationale de la Recherche ANR-15-IDEX-02 and G7H-IRG23D06
6 · The paper itself

Abstract

A cell's ability to secrete extracellular vesicles (EVs) for communication is present in all three domains of life. Notably, Gram-negative bacteria produce a specific type of EVs called outer membrane vesicles (OMVs). We previously observed the presence of OMVs in human blood, which could represent a means of communication from the microbiota to the host. Here, in order to investigate the possible translocation of OMVs from the intestine to other organs, the mouse was used as an animal model after OMVs administration. To achieve this, we first optimized the signal of OMVs containing the fluorescent protein miRFP713 associated with the outer membrane anchoring peptide OmpA by adding biliverdin, a fluorescence cofactor, to the cultures. The miRFP713-expressing OMVs produced in

Indexed as

Escherichia coliExtracellular VesiclesAnimalsBacterial Outer Membrane ProteinsGram-Negative BacteriaHumansIntestinesMiceTissue DistributionBacterial Outer Membrane Proteinsbiodistributionextracellular vesicleslive imagingmicrobiotamiRFP713outer membrane vesicles (OMVs)

Identifiers

PMID38339099
PMCPMC10855177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.