Evidence map›Paper›PMID 38339061›Full record

ArticleInternational journal of molecular sciences2024

Anti-Inflammatory and Antioxidant Pyrrolo[3,4-

Aleksandra Kotynia, Edward Krzyżak, Julia Żądło, Maja Witczak, Łukasz Szczukowski, Jakub Mucha, Piotr Świątek, Aleksandra Marciniak

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Novel Isoxazole-Based Antifungal Drug Candidates.International journal of molecular sciences · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aleksandra KotyniaDepartment of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.ORCID 0000-0003-0730-8975
Edward KrzyżakDepartment of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.ORCID 0000-0002-5000-2448
Julia Żądło"Biomolecule" Student Science Club, Department of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.
Maja Witczak"Biomolecule" Student Science Club, Department of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.
Łukasz SzczukowskiDepartment of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.ORCID 0000-0002-9768-6269
Jakub MuchaFaculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.
Piotr ŚwiątekDepartment of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.ORCID 0000-0003-4613-025X
Aleksandra MarciniakDepartment of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.ORCID 0000-0003-2225-7897
Wroclaw Medical University · PL

Funding

ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
NIGMS NIH HHS R01 GM129325Wroclaw Medical University SUBZ.D290.24.041
6 · The paper itself

Abstract

From the point of view of the search for new pharmaceuticals, pyridazinone derivatives are a very promising group of compounds. In our previous works, we have proved that newly synthesized ligands from this group have desirable biological and pharmacokinetic properties. Therefore, we decided to continue the research evaluating the activity of pyrrolo[3,4-

Indexed as

Anti-Inflammatory AgentsAntioxidantsBlood ProteinsDNAModels, MolecularMolecular Docking SimulationAnti-Inflammatory AgentsAntioxidantsBlood ProteinsDNACD spectroscopyDNAfluorescence spectroscopymolecular modellingplasma proteinspyridazinone derivatives

Identifiers

PMID38339061
PMCPMC10855066
OpenAlexW4391433962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.