Evidence map›Paper›PMID 38339034›Full record

ArticleInternational journal of molecular sciences2024

Transcriptome Analysis in Mexican Adults with Acute Lymphoblastic Leukemia.

Gabriela Marisol Cruz-Miranda, Irma Olarte-Carrillo, Diego Alberto Bárcenas-López, Adolfo Martínez-Tovar, Julian Ramírez-Bello, Christian Omar Ramos-Peñafiel, Anel Irais García-Laguna, Rafael Cerón-Maldonado, Didier May-Hau, Silvia Jiménez-Morales

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

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  8. Expression ofFrontiers in oncology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Gabriela Marisol Cruz-MirandaPrograma de Doctorado, Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0001-6295-6698
Irma Olarte-CarrilloLaboratorio de Biología Molecular, Servicio de Hematología, Hospital General de México Dr. Eduardo Liceaga, Mexico City 06720, Mexico.ORCID 0000-0002-5374-0534
Diego Alberto Bárcenas-LópezPrograma de Doctorado, Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Adolfo Martínez-TovarLaboratorio de Biología Molecular, Servicio de Hematología, Hospital General de México Dr. Eduardo Liceaga, Mexico City 06720, Mexico.ORCID 0000-0002-5713-3731
Julian Ramírez-BelloSubdirección de Investigación Clínica, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.
Christian Omar Ramos-PeñafielDepartamento de Hematología, Hospital General de México Dr. Eduardo Liceaga, Mexico City 06720, Mexico.
Anel Irais García-LagunaLaboratorio de Biología Molecular, Servicio de Hematología, Hospital General de México Dr. Eduardo Liceaga, Mexico City 06720, Mexico.
Rafael Cerón-MaldonadoPrograma de Doctorado, Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0003-0935-4107
Didier May-HauLaboratorio de Innovación en Medicina de Precisión Núcleo A, Instituto Nacional de Medicina Genómica, Mexico City 14610, Mexico.ORCID 0000-0002-7671-7310
Silvia Jiménez-MoralesLaboratorio de Innovación en Medicina de Precisión Núcleo A, Instituto Nacional de Medicina Genómica, Mexico City 14610, Mexico.ORCID 0000-0002-6590-9712
Hospital General de México · MXNational Institute of Genomic Medicine · MXInstituto Nacional de Cardiología · MX

Funding

Consejo Nacional de Humanidades, Ciencias y Tecnologías 2018-000012-01NACF
6 · The paper itself

Abstract

Acute lymphoblastic leukemia (ALL) represents around 25% of adult acute leukemias. Despite the increasing improvement in the survival rate of ALL patients during the last decade, the heterogeneous clinical and molecular features of this malignancy still represent a major challenge for treatment and achieving better outcomes. To identify aberrantly expressed genes in bone marrow (BM) samples from adults with ALL, transcriptomic analysis was performed using Affymetrix Human Transcriptome Array 2.0 (HTA 2.0). Differentially expressed genes (DEGs) (±2-fold change,

Indexed as

Gene Expression ProfilingPrecursor Cell Lymphoblastic Leukemia-LymphomaBiomarkersComputational BiologyHumansRecurrenceSOXC Transcription FactorsTranscriptomeBiomarkersSOX4 protein, humanSOXC Transcription Factorsacute lymphoblastic leukemiaadultsmexican patientsmicroarraystranscriptome analysis

Identifiers

PMID38339034
PMCPMC10855968
OpenAlexW4391449721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.