Evidence map›Paper›PMID 38338972›Full record

Observational studyInternational journal of molecular sciences2024

Assessing the Impact of Long-Term High-Dose Statin Treatment on Pericoronary Inflammation and Plaque Distribution-A Comprehensive Coronary CTA Follow-Up Study.

Botond Barna Mátyás, Imre Benedek, Nóra Raț, Emanuel Blîndu, Zsolt Parajkó, Theofana Mihăilă, Theodora Benedek

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  3. Observational
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  5. Article
  6. Review
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  8. Review
  9. Review
  10. CT coronary angiography in the lipid clinic: a pilot study and lipidologist survey.The international journal of cardiovascular imaging · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
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  16. Article
  17. Article
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Botond Barna MátyásClinic of Cardiology, Mureș County Emergency Clinical Hospital, 540136 Târgu Mureș, Romania.ORCID 0000-0002-0775-1566
Imre BenedekClinic of Cardiology, Mureș County Emergency Clinical Hospital, 540136 Târgu Mureș, Romania.
Nóra RațClinic of Cardiology, Mureș County Emergency Clinical Hospital, 540136 Târgu Mureș, Romania.ORCID 0000-0001-6975-5987
Emanuel BlînduClinic of Cardiology, Mureș County Emergency Clinical Hospital, 540136 Târgu Mureș, Romania.
Zsolt ParajkóClinic of Cardiology, Mureș County Emergency Clinical Hospital, 540136 Târgu Mureș, Romania.
Theofana MihăilăClinic of Cardiology, Mureș County Emergency Clinical Hospital, 540136 Târgu Mureș, Romania.
Theodora BenedekClinic of Cardiology, Mureș County Emergency Clinical Hospital, 540136 Târgu Mureș, Romania.
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · RO

Funding

CATECHOLAMINES AND REPRODUCTIVE AGINGR01AG002021 · NIA · UNIVERSITY OF FLORIDA · PI SIMPKINS, JAMES W. · 1985 to 1990
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Romanian Ministry of Education - UEFISCDI PCE 206/2021
6 · The paper itself

Abstract

Computed tomography angiography (CTA) has validated the use of pericoronary adipose tissue (PCAT) attenuation as a credible indicator of coronary inflammation, playing a crucial role in coronary artery disease (CAD). This study aimed to evaluate the long-term effects of high-dose statins on PCAT attenuation at coronary lesion sites and changes in plaque distribution. Our prospective observational study included 52 patients (mean age 60.43) with chest pain, a low-to-intermediate likelihood of CAD, who had documented atheromatous plaque through CTA, performed approximately 1 year and 3 years after inclusion. We utilized the advanced features of the CaRi-Heart

Indexed as

Coronary Artery DiseaseHydroxymethylglutaryl-CoA Reductase InhibitorsPlaque, AtheroscleroticAdipose TissueComputed Tomography AngiographyCoronary AngiographyCoronary VesselsFollow-Up StudiesHumansInflammationMiddle AgedHydroxymethylglutaryl-CoA Reductase Inhibitorsatherosclerosiscomputed tomography angiographycoronary artery diseasefat attenuation index scorehigh-dose statinpericoronary adipose tissue inflammation

Identifiers

PMID38338972
PMCPMC10855947
OpenAlexW4391361203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.