Evidence map›Paper›PMID 38338954›Full record

Trial reportInternational journal of molecular sciences2024

Annurca Apple Oleolite as Functional Ingredient for the Formulation of Cosmetics with Skin-Antiaging Activity.

Ritamaria Di Lorenzo, Maria Maisto, Lucia Ricci, Vincenzo Piccolo, Adua Marzocchi, Giovanni Greco, Gian Carlo Tenore, Sonia Laneri

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. NAD-Driven Sirtuin Activation byInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ritamaria Di LorenzoRD Cosmetics, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0003-1406-6214
Maria MaistoChimNutra Labs, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-0340-2254
Lucia RicciRD Cosmetics, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.
Vincenzo PiccoloChimNutra Labs, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0003-4480-5022
Adua MarzocchiChimNutra Labs, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.
Giovanni GrecoRD Cosmetics, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.
Gian Carlo TenoreChimNutra Labs, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-0251-9936
Sonia LaneriRD Cosmetics, Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-1173-1592

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification of natural remedies for the management of the skin aging process is an increasingly growing issue. In this context, ursolic acid (UA), a ubiquitous molecule, mainly contained in Annurca apple (AA) fruit, has demonstrated valuable cosmetic potential. To this end, in the current study, the AA oleolite (AAO, extract in sunflower oil containing 784.40 ± 7.579 µg/mL of UA) was evaluated to inhibit porcine elastase enzymatic reactions through a validated spectrophotometric method. AAO has shown a valuable capacity to contrast the elastase enzyme with a calculated IC

Indexed as

CosmeticsMalusSkin AgingAnimalsAntioxidantsHumansPancreatic ElastasePharmaceutical VehiclesSkinSwineAntioxidantsCosmeticsPancreatic ElastasePharmaceutical VehiclesAnnurca appleantiagingcosmeceuticalselastase inhibitionoleolitetopical formulationursolic acidwrinkles

Identifiers

PMID38338954
PMCPMC10855134

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.