ReviewInternational journal of molecular sciences2024
The Role of Protein Degradation in Estimation Postmortem Interval and Confirmation of Cause of Death in Forensic Pathology: A Literature Review.
Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Artificial intelligence in forensic science: a systematic review. Part II: long-range postmortem interval estimation.International journal of legal medicine · 2026Pooled it
- The Role of Cardiac Troponins in Postmortem Diagnosis of Myocardial Ischemia: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Integrated renal histopathology, RNA decay, and protein degradation signatures enhance post-mortem interval prediction using machine-learning models in a veterinary forensic rat model.Veterinary world · 2026Article
- Benefits and Limitations Associated with the Use of Alternative Biological Matrices in Forensic Toxicology, as Well as Genetic Markers of Poisoning and Psychoactive Substance Abuse.International journal of molecular sciences · 2026Review
- Serum S100B level as biomarker of traumatic deaths: correlations with injury patterns and postmortem interval.Forensic science, medicine, and pathology · 2026Article
- Colocalization and discordance between plasma and brain protein quantitative trait loci.bioRxiv : the preprint server for biology · 2026Article
- Article
- Postmortem interval estimation through skeletal muscle protein degradation: a comprehensive review.International journal of legal medicine · 2026Review
- Diagnostic utility of postmortem serum tumor markers for identifying primary malignancies: A forensic evaluation of six markers.Forensic science, medicine, and pathology · 2026Article
- Augmented and virtual reality in surgical practice: a review of applications in visualization, training, and future directions.Journal of robotic surgery · 2026Review
- Molecular biology research progress in post-mortem interval (PMI) estimation in forensic medicine.International journal of legal medicine · 2026Review
- Postmortem interval estimation based on protein analysis and marker studies in different organs in vivo.Forensic science, medicine, and pathology · 2025Article
- A novel method for assessing postmortem interval using radon radioisotopic decay - an internal radon 'time of death clock'.Scientific reports · 2025Article
- Review
- Decoding Time of Death: Histopathological Dynamics of Intervertebral Discs as a Novel Marker for Postmortem Interval Estimation.Diagnostics (Basel, Switzerland) · 2025Article
- Influence of Drugs and Toxins on Decomposition Dynamics: Forensic Implications.Molecules (Basel, Switzerland) · 2024Review
- Post-mortem Interval estimate based on dental pulp: A histomorphology approach.The Journal of forensic odonto-stomatology · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well known that proteins are important bio-macromolecules in human organisms, and numerous proteins are widely used in the clinical practice, whereas their application in forensic science is currently limited. This limitation is mainly attributed to the postmortem degradation of targeted proteins, which can significantly impact final conclusions. In the last decade, numerous methods have been established to detect the protein from a forensic perspective, and some of the postmortem proteins have been applied in forensic practice. To better understand the emerging issues and challenges in postmortem proteins, we have reviewed the current application of protein technologies at postmortem in forensic practice. Meanwhile, we discuss the application of proteins in identifying the cause of death, and postmortem interval (PMI). Finally, we highlight the interpretability and limitations of postmortem protein challenges. We believe that utilizing the multi-omics method can enhance the comprehensiveness of applying proteins in forensic practice.
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Registered trials
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