Evidence map›Paper›PMID 38338919›Full record

ReviewInternational journal of molecular sciences2024

Clinical Application of Liquid Biopsy in Pancreatic Cancer: A Narrative Review.

Elena Ramírez-Maldonado, Sandra López Gordo, Rui Pedro Major Branco, Mihai-Calin Pavel, Laia Estalella, Erik Llàcer-Millán, María Alejandra Guerrero, Estrella López-Gordo, Robert Memba, Rosa Jorba

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Review
  3. Proteomics in pancreatic cancer.Biomarker research · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Elena Ramírez-MaldonadoHBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.
Sandra López GordoGeneral Surgery Department, Maresme Health Consortium, 08304 Mataro, Spain.
Rui Pedro Major BrancoGeneral Surgery at Garcia de Orta's Hospital, 2805-267 Almada, Portugal.
Mihai-Calin PavelHBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.
Laia EstalellaHBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.
Erik Llàcer-MillánHBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.ORCID 0000-0003-4178-1408
María Alejandra GuerreroHBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.ORCID 0000-0002-5886-4018
Estrella López-GordoAffinia Therapeutics Inc., Waltham, MA 02453, USA.ORCID 0000-0001-8737-5419
Robert MembaHBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.
Rosa JorbaHBP Unit, General Surgery Department, Joan XXIII University Hospital, 43005 Tarragona, Spain.ORCID 0000-0003-3307-4340
Hospital Universitari Joan XXIII de Tarragona · ESHospital Garcia de Orta · PTMaresme Health Consortium · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma contributes significantly to global cancer-related deaths, featuring only a 10% survival rate over five years. The quest for novel tumor markers is critical to facilitate early diagnosis and tailor treatment strategies for this disease, which is key to improving patient outcomes. In pancreatic ductal adenocarcinoma, these markers have been demonstrated to play a crucial role in early identification, continuous monitoring, and prediction of its prognosis and have led to better patient outcomes. Nowadays, biopsy specimens serve to ascertain diagnosis and determine tumor type. However, liquid biopsies present distinct advantages over conventional biopsy techniques. They offer a noninvasive, easily administered procedure, delivering insights into the tumor's status and facilitating real-time monitoring. Liquid biopsies encompass a variety of elements, such as circulating tumor cells, circulating tumor DNA, extracellular vesicles, microRNAs, circulating RNA, tumor platelets, and tumor endothelial cells. This review aims to provide an overview of the clinical applications of liquid biopsy as a technique in the management of pancreatic cancer.

Indexed as

Carcinoma, Pancreatic DuctalNeoplastic Cells, CirculatingPancreatic NeoplasmsBiomarkers, TumorDNA, NeoplasmEndothelial CellsHumansLiquid BiopsyBiomarkers, TumorDNA, Neoplasmcirculating free tumor DNAcirculating tumor cellscirculating tumor DNAextracellular vesiclesliquid biopsypancreatic ductal adenocarcinoma

Identifiers

PMID38338919
PMCPMC10855073
OpenAlexW4391323232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.