Evidence map›Paper›PMID 38338834›Full record

ArticleInternational journal of molecular sciences2024

Bioinformatics and Experimental Validation for Identifying Biomarkers Associated with AMG510 (Sotorasib) Resistance in KRAS

Peng Lin, Wei Cheng, Xin Qi, Pinglu Zhang, Jianshe Xiong, Jing Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Peng LinKey Laboratory of Marine Drugs, Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.ORCID 0009-0009-3398-8864
Wei ChengKey Laboratory of Marine Drugs, Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Xin QiKey Laboratory of Marine Drugs, Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Pinglu ZhangFaculty of Information Science and Engineering, Ocean University of China, Qingdao 266003, China.
Jianshe XiongFaculty of Information Science and Engineering, Ocean University of China, Qingdao 266003, China.
Jing LiKey Laboratory of Marine Drugs, Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Qingdao National Laboratory for Marine Science and Technology · CNOcean University of China · CN

Funding

Hainan Provincial Joint Project of Sanya Yazhou Bay Science and Technology City 2021CXLH0012Shandong Provincial Natural Science Foundation ZR2022MH083Shandong Provincial Natural Science Foundation (major basic research projects) ZR2021ZD28
6 · The paper itself

Abstract

The Kirsten rat sarcoma viral oncogene homolog (KRAS)

Indexed as

Adenocarcinoma of LungF-Box ProteinsLung NeoplasmsPiperazinesPyridinesPyrimidinesBiomarkersComputational BiologyHumansMutationNeoplasm ProteinsProto-Oncogene Proteins p21(ras)Transcription FactorsTumor MicroenvironmentBiomarkersFAM83A protein, humanF-Box ProteinsFBXO44 protein, humanKRAS protein, humanNeoplasm ProteinsPiperazinesProto-Oncogene Proteins p21(ras)PyridinesPyrimidinessotorasibTranscription FactorsAMG510 (Sotorasib)biomarkerslung adenocarcinomaresistancesingle-cell transcriptomics

Identifiers

PMID38338834
PMCPMC10855101
OpenAlexW4391263015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.