Evidence map›Paper›PMID 38338793›Full record

ArticleInternational journal of molecular sciences2024

Kisspeptin-10 Improves Testicular Redox Status but Does Not Alter the Unfolded Protein Response (UPR) That Is Downregulated by Hypothyroidism in a Rat Model.

Luciano Cardoso Santos, Jeane Martinha Dos Anjos Cordeiro, Maria Clara da Silva Galrão Cunha, Bianca Reis Santos, Luciana Santos de Oliveira, Adriana Lopes da Silva, Erikles Macêdo Barbosa, Raquel Vieira Niella, Gustavo José Cota de Freitas, Daniel de Assis Santos and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Luciano Cardoso SantosElectron Microscopy Center, Department of Biological Sciences, State University of Santa Cruz, Campus Soane Nazare de Andrade, Ilheus 45662-900, Brazil.ORCID 0000-0001-7679-1353
Jeane Martinha Dos Anjos CordeiroElectron Microscopy Center, Department of Biological Sciences, State University of Santa Cruz, Campus Soane Nazare de Andrade, Ilheus 45662-900, Brazil.ORCID 0000-0002-7209-6043
Maria Clara da Silva Galrão CunhaElectron Microscopy Center, Department of Biological Sciences, State University of Santa Cruz, Campus Soane Nazare de Andrade, Ilheus 45662-900, Brazil.
Bianca Reis SantosElectron Microscopy Center, Department of Biological Sciences, State University of Santa Cruz, Campus Soane Nazare de Andrade, Ilheus 45662-900, Brazil.ORCID 0000-0001-7587-6662
Luciana Santos de OliveiraElectron Microscopy Center, Department of Biological Sciences, State University of Santa Cruz, Campus Soane Nazare de Andrade, Ilheus 45662-900, Brazil.
Adriana Lopes da SilvaElectron Microscopy Center, Department of Biological Sciences, State University of Santa Cruz, Campus Soane Nazare de Andrade, Ilheus 45662-900, Brazil.ORCID 0009-0007-8242-3267
Erikles Macêdo BarbosaElectron Microscopy Center, Department of Biological Sciences, State University of Santa Cruz, Campus Soane Nazare de Andrade, Ilheus 45662-900, Brazil.
Raquel Vieira NiellaVeterinary Hospital, Department of Agricultural and Environmental Sciences, State University of Santa Cruz, Campus Soane Nazare de Andrade, Ilheus 45662-900, Brazil.ORCID 0000-0003-3544-1757
Gustavo José Cota de FreitasDepartment of Microbiology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Daniel de Assis SantosDepartment of Microbiology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0002-1108-5666
Rogéria SerakidesDepartment of Veterinary Clinic and Surgery, Veterinary School, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0001-5374-6242
Natália de Melo OcarinoDepartment of Veterinary Clinic and Surgery, Veterinary School, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0002-9542-4759
Stephanie Carvalho BorgesElectron Microscopy Center, Department of Biological Sciences, State University of Santa Cruz, Campus Soane Nazare de Andrade, Ilheus 45662-900, Brazil.ORCID 0000-0002-2534-143X
Mário Sérgio Lima de LavorVeterinary Hospital, Department of Agricultural and Environmental Sciences, State University of Santa Cruz, Campus Soane Nazare de Andrade, Ilheus 45662-900, Brazil.ORCID 0000-0003-0795-5320
Juneo Freitas SilvaElectron Microscopy Center, Department of Biological Sciences, State University of Santa Cruz, Campus Soane Nazare de Andrade, Ilheus 45662-900, Brazil.ORCID 0000-0002-9881-1236
Universidade Estadual de Santa Cruz · BRUniversidade Federal de Minas Gerais · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 2019State University of Santa Cruz 073.11014.2022.0001637-78
6 · The paper itself

Abstract

Hypothyroidism compromises the testicular redox status and is associated with reduced sperm quality and infertility in men. In this regard, studies have demonstrated the antioxidant potential of kisspeptin in reproductive and metabolic diseases. In this study, we evaluate the effects of kisspeptin-10 (Kp10) on the testicular redox, as well as mediators of the unfolded protein response (UPR) in adult rats with hypothyroidism. Adult male Wistar rats were randomly separated into the Control (

Indexed as

AntioxidantsHypothyroidismAnimalsEndoplasmic Reticulum Chaperone BiPHumansKisspeptinsMaleOxidation-ReductionOxidative StressPeroxynitrous AcidRatsRats, WistarSemenSuperoxide Dismutase-1TestisThiobarbituric Acid Reactive SubstancesAntioxidantsEndoplasmic Reticulum Chaperone BiPKISS1 protein, humanKisspeptinsPeroxynitrous AcidSuperoxide Dismutase-1Thiobarbituric Acid Reactive Substancesmaleoxidative stressratreticular stressthyroid

Identifiers

PMID38338793
PMCPMC10855899
OpenAlexW4391259181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.