Identification of the Major Facilitator Superfamily Efflux Pump KpsrMFS in

Wei He, Minzhi Jiang, Ying Li, Xizhen Ge

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.7field-weighted citation impact, top 38% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wei HeCollege of Biochemical Engineering, Beijing Union University, Beijing 100023, China.

Minzhi JiangCollege of Biochemical Engineering, Beijing Union University, Beijing 100023, China.

Ying LiCollege of Biochemical Engineering, Beijing Union University, Beijing 100023, China.ORCID 0000-0001-8321-022X

Xizhen GeCollege of Biochemical Engineering, Beijing Union University, Beijing 100023, China.

Beijing Union University · CN

Funding

Beijing Municipal Government BPHR202203209

6 · The paper itself

Abstract

Efflux pumps play important roles in bacterial detoxification and some of them are stress-response elements that are up-regulated when the host is treated with antibiotics. However, efflux pumps that are down-regulated by stimulations are rarely discovered. Herein, we analyzed multiple transcriptome data and discovered a special (Major Facilitator Superfamily) MFS efflux pump, KpsrMFS, from

Indexed as

Bacterial ProteinsKlebsiella pneumoniaeAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialMembrane Transport ProteinsMicrobial Sensitivity TestsReactive Oxygen SpeciesAnti-Bacterial AgentsBacterial ProteinsMembrane Transport ProteinsReactive Oxygen Speciesantibiotic resistancedown-regulatedefflux pumpKlebsiella pneumoniaereactive oxygen species

Identifiers

PMID38338743

DOI10.3390/ijms25031466

PMCPMC10855805

OpenAlexW4391229018

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.