Evidence map›Paper›PMID 38338706›Full record

ArticleInternational journal of molecular sciences2024

Telomere Length, Mitochondrial DNA, and Micronucleus Yield in Response to Oxidative Stress in Peripheral Blood Mononuclear Cells.

Andrea Borghini, Rudina Ndreu, Paola Canale, Jonica Campolo, Irene Marinaro, Antonella Mercuri, Stefano Turchi, Maria Grazia Andreassi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Improving our understanding of the biology of aging: findings from the Age-It Research Program.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Andrea BorghiniCNR Institute of Clinical Physiology, 56124 Pisa, Italy.ORCID 0000-0003-1061-8309
Rudina NdreuCNR Institute of Clinical Physiology, 56124 Pisa, Italy.ORCID 0000-0003-1198-9822
Paola CanaleCNR Institute of Clinical Physiology, 56124 Pisa, Italy.
Jonica CampoloCNR Institute of Clinical Physiology, ASST Grande Ospedale Metropolitano Niguarda, 20142 Milan, Italy.ORCID 0000-0002-1711-6216
Irene MarinaroCNR Institute of Clinical Physiology, 56124 Pisa, Italy.
Antonella MercuriCNR Institute of Clinical Physiology, 56124 Pisa, Italy.
Stefano TurchiCNR Institute of Clinical Physiology, 56124 Pisa, Italy.
Maria Grazia AndreassiCNR Institute of Clinical Physiology, 56124 Pisa, Italy.ORCID 0000-0002-2163-0816
Istituto di Fisiologia Clinica · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITScuola Superiore Sant'Anna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telomere shortening, chromosomal damage, and mitochondrial dysfunction are major initiators of cell aging and biomarkers of many diseases. However, the underlying correlations between nuclear and mitochondrial DNA alterations remain unclear. We investigated the relationship between telomere length (TL) and micronucleus (MN) and their association with mitochondrial DNA copy number (mtDNAcn) in peripheral blood mononuclear cells (PBMCs) in response to 100 μM and 200 μM of hydrogen peroxide (H

Indexed as

DNA, MitochondrialLeukocytes, MononuclearDNA Copy Number VariationsHydrogen PeroxideMitochondriaOxidative StressTelomereTelomere ShorteningDNA, MitochondrialHydrogen Peroxidechromosomal damagehydrogen peroxidemicronucleusmitochondrial DNA copy numberoxidative stressperipheral blood mononuclear cellstelomere length

Identifiers

PMID38338706
PMCPMC10855977
OpenAlexW4391173702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.