Evidence map›Paper›PMID 38338469›Full record

ReviewMolecules (Basel, Switzerland)2024

Natural Compounds in Non-Melanoma Skin Cancer: Prevention and Treatment.

Szymon Kowalski, Julia Karska, Maciej Tota, Katarzyna Skinderowicz, Julita Kulbacka, Małgorzata Drąg-Zalesińska

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Local Delivery of Ginger ExtractCurrent drug delivery · 2026
    Article
  7. Review
  8. Review
  9. Gels (Basel, Switzerland) · 2025
    Review
  10. Cellular and Molecular Effects of Magnetic Fields.International journal of molecular sciences · 2024
    Review
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Szymon KowalskiFaculty of Medicine, Wroclaw Medical University, Pasteura 1, 50-367 Wroclaw, Poland.
Julia KarskaDepartment of Psychiatry, Wroclaw Medical University, Pasteura 10, 50-367 Wroclaw, Poland.ORCID 0009-0001-4869-5943
Maciej TotaFaculty of Medicine, Wroclaw Medical University, Pasteura 1, 50-367 Wroclaw, Poland.ORCID 0000-0002-5298-6479
Katarzyna SkinderowiczFaculty of Medicine, Wroclaw Medical University, Pasteura 1, 50-367 Wroclaw, Poland.ORCID 0009-0002-9083-3593
Julita KulbackaDepartment of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.ORCID 0000-0001-8272-5440
Małgorzata Drąg-ZalesińskaDepartment of Human Morphology and Embryology, Division of Histology and Embryology, Faculty of Medicine, Wroclaw Medical University, T. Chalubińskiego 6a, 50-368 Wroclaw, Poland.ORCID 0000-0001-6180-9557

Funding

Statutory Subsidy Funds of the Department of Molecular and Cellular Biology SUBZ.D260.23.018
6 · The paper itself

Abstract

The elevated occurrence of non-melanoma skin cancer (NMSC) and the adverse effects associated with available treatments adversely impact the quality of life in multiple dimensions. In connection with this, there is a necessity for alternative approaches characterized by increased tolerance and lower side effects. Natural compounds could be employed due to their safety profile and effectiveness for inflammatory and neoplastic skin diseases. These anti-cancer drugs are often derived from natural sources such as marine, zoonotic, and botanical origins. Natural compounds should exhibit anti-carcinogenic actions through various pathways, influencing apoptosis potentiation, cell proliferation inhibition, and metastasis suppression. This review provides an overview of natural compounds used in cancer chemotherapies, chemoprevention, and promotion of skin regeneration, including polyphenolic compounds, flavonoids, vitamins, alkaloids, terpenoids, isothiocyanates, cannabinoids, carotenoids, and ceramides.

Indexed as

Antineoplastic AgentsSkin NeoplasmsCarotenoidsChemopreventionHumansQuality of LifeAntineoplastic AgentsCarotenoidsnatural agentsnatural compoundsNMSCnon-melanoma skin cancer

Identifiers

PMID38338469
PMCPMC10856721

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.