Evidence map›Paper›PMID 38338393›Full record

ArticleMolecules (Basel, Switzerland)2024

Synthesis and Evaluation of Antimicrobial Activity of the Rearranged Abietane Prattinin A and Its Synthetic Derivatives.

Mustapha Ait El Had, Manal Zefzoufi, Houda Zentar, Lahoucine Bahsis, Mouhi Eddine Hachim, Adib Ghaleb, Choukri Khelifa-Mahdjoubi, Hafida Bouamama, Ramón Alvarez-Manzaneda, José Justicia and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mustapha Ait El HadDepartamento de Química Organica, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0002-2619-8479
Manal ZefzoufiRecherche en Développement Durable et Santé, Faculté des Sciences et Techniques, Cadi Ayyad University, Marrakech 40000, Morocco.ORCID 0000-0002-0255-5443
Houda ZentarDepartamento de Química Organica, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain.
Lahoucine BahsisLaboratory of Analytical and Molecular Chemistry, Polydisciplinary Faculty, Cadi Ayyad University, BP 4162, Safi 46000, Morocco.ORCID 0000-0002-7252-6680
Mouhi Eddine HachimLaboratory of Analytical and Molecular Chemistry, Polydisciplinary Faculty, Cadi Ayyad University, BP 4162, Safi 46000, Morocco.ORCID 0000-0001-7692-5323
Adib GhalebLaboratory of Analytical and Molecular Chemistry, Polydisciplinary Faculty, Cadi Ayyad University, BP 4162, Safi 46000, Morocco.ORCID 0000-0002-0243-342X
Choukri Khelifa-MahdjoubiDepartamento de Química Organica, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0002-6009-7989
Hafida BouamamaRecherche en Développement Durable et Santé, Faculté des Sciences et Techniques, Cadi Ayyad University, Marrakech 40000, Morocco.ORCID 0000-0002-2739-5896
Ramón Alvarez-ManzanedaÁrea de Química Orgánica, Departamento de Química y Física, Universidad de Almería, 04120 Almería, Spain.
José JusticiaDepartamento de Química Organica, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0002-7712-0911
Rachid ChahbounDepartamento de Química Organica, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0001-5303-1183

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthesis of the natural product prattinin A and some new derivatives has been achieved using abietic acid. The final products and a selection of intermediates were evaluated for their antibacterial activity against three human pathogenic bacteria:

Indexed as

Anti-Infective AgentsStaphylococcus aureusAbietanesAnti-Bacterial AgentsEscherichia coliHumansMicrobial Sensitivity TestsMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipabietaneAbietanesAnti-Bacterial AgentsAnti-Infective Agentsabietane rearrangedADMETantibacterial activityDFT calculationmolecular dockingnatural productprattinin A

Identifiers

PMID38338393
PMCPMC10856147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.