Evidence map›Paper›PMID 38338373›Full record

ArticleMolecules (Basel, Switzerland)2024

Cytotoxicity Enhancement in Osteosarcoma with Multifunctional I-131 Radiotherapeutic Nanoparticles: In Vitro Three-Dimensional Spheroid Model and Release Kinetics Modeling.

Suphalak Khamruang Marshall, Maneerat Taweesap, Boonyisa Saelim, Verachai Pachana, Nadeeya Benlateh, Sireetorn Sangangam, Achiraya Bumrungsin, Haswanee Kholo-Asae, Issaree Wongtechanon

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Suphalak Khamruang MarshallDepartment of Radiology, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.ORCID 0000-0002-0481-3688
Maneerat TaweesapDepartment of Radiology, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.
Boonyisa SaelimDepartment of Radiology, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.
Verachai PachanaDepartment of Radiology, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.
Nadeeya BenlatehDepartment of Radiology, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.
Sireetorn SangangamDepartment of Radiology, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.
Achiraya BumrungsinDepartment of Radiology, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.
Haswanee Kholo-AsaeDepartment of Radiology, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.
Issaree WongtechanonDepartment of Radiology, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.
Prince of Songkla University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This novel radiolabeled chitosan nanoparticle, facilitated with curcumin, increased doxorubicin cytotoxicity and radiosensitivity to MG-63 osteosarcoma cells in a three-dimensional model. Delivery of the anti-epidermal growth factor receptor (EGFR) targeted carboxymethyl chitosan nanoparticles, directly labeled with Na

Indexed as

Bone NeoplasmsChitosanCurcuminNanoparticlesOsteosarcomaCell Line, TumorDoxorubicinDrug CarriersErbB ReceptorsHumansIodine RadioisotopesChitosanCurcuminDoxorubicinDrug CarriersErbB ReceptorsIodine-131Iodine Radioisotopesanticancerchitosancurcumincytotoxicitydoxorubicinfractionated doseI-131nanoparticleosteosarcomaradiosensitivity

Identifiers

PMID38338373
PMCPMC10856476
OpenAlexW4391360899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.