Evidence map›Paper›PMID 38338356›Full record

ArticleMolecules (Basel, Switzerland)2024

Exploring the Therapeutic Efficacy of Parsley (

Mariana Ganea, Laura Grațiela Vicaș, Octavia Gligor, Ioan Sarac, Emilian Onisan, Csaba Nagy, Corina Moisa, Timea Claudia Ghitea

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Emulgel withPharmaceuticals (Basel, Switzerland) · 2025
    Article
  8. Frontiers in pharmacology · 2025
    Article
  9. Review
  10. In Vitro Screening of Ecotoxic and Cytotoxic Activities ofInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Mariana GaneaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 1st Decembrie Street, 410073 Oradea, Romania.ORCID 0000-0003-4643-2151
Laura Grațiela VicașDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 1st Decembrie Street, 410073 Oradea, Romania.ORCID 0000-0001-5328-333X
Octavia GligorFaculty of Pharmacy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.ORCID 0000-0002-6672-1535
Ioan SaracDepartment of Genetic Engineering, University of Life Sciences "King Mihai I Timișoara", 300645 Timișoara, Romania.
Emilian OnisanDepartment of Genetic Engineering, University of Life Sciences "King Mihai I Timișoara", 300645 Timișoara, Romania.
Csaba NagyIndependent Researcher, 417595 Tinca, Romania.
Corina MoisaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 1st Decembrie Street, 410073 Oradea, Romania.
Timea Claudia GhiteaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 1st Decembrie Street, 410073 Oradea, Romania.ORCID 0000-0001-8981-1958
University of Oradea · ROWest University of Timişoara · ROIuliu Hațieganu University of Medicine and Pharmacy · RORomanian Space Agency · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The status of parsley as a well-known folk medicine noted for its nutritional and medicinal properties prompted the exploration of its potential as a functional food and natural remedy. The paper aims to investigate the potential of parsley to enhance muscle function and alleviate psoriasiform dermatitis, eventually establishing it as a natural, well-tolerated alternative with specific benefits for both muscles and skin. This study examines the tolerability of parsley in a cohort of 937 participants by assessing immunoglobulin G (IgG) reactions. The findings reveal high tolerability, as 96.26% of participants experienced no adverse effects. Among the 902 individuals lacking hypersensitivity, 37.02% reported muscle cramps, with a notable 15.02% reduction observed in the subgroup consuming parsley juice. In the subset of 32 subjects with dermatitis, the application of parsley extract ointment led to a significant decrease in dermatological parameters (redness, thickness, scaling). While the control group exhibited improvements, statistical significance was not observed. Notably, four categories of affected area reduction were identified, with scaling demonstrating the most pronounced impact. The results propose that parsley holds promise for favorable tolerability, contributing to the alleviation of muscle cramps and presenting an effective alternative in dermatitis treatment. Nonetheless, sustained validation through long-term studies is imperative to substantiate these preliminary findings.

Indexed as

DermatitisFunctional FoodHumansMuscle CrampPetroselinumPlant ExtractsPlant ExtractsdermatitisIgG reactionsmuscle crampsparsleyPetroselinum crispum Mill.

Identifiers

PMID38338356
PMCPMC10856782
OpenAlexW4391352073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.