Evidence map›Paper›PMID 38338343›Full record

ReviewMolecules (Basel, Switzerland)2024

Prevention and Potential Treatment Strategies for Respiratory Syncytial Virus.

Bo-Wen Sun, Peng-Peng Zhang, Zong-Hao Wang, Xia Yao, Meng-Lan He, Rui-Ting Bai, Hao Che, Jing Lin, Tian Xie, Zi Hui and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Bo-Wen SunSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Peng-Peng ZhangSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Zong-Hao WangSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Xia YaoSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Meng-Lan HeSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Rui-Ting BaiSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Hao CheSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Jing LinDrug Discovery, Hangzhou Haolu Pharma Co., Hangzhou 311121, China.
Tian XieSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.ORCID 0000-0001-7066-1443
Zi HuiSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Xiang-Yang YeSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.ORCID 0000-0003-3739-0930
Li-Wei WangSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Hangzhou Normal University · CN

Funding

General scientific research project of department of education of Zhejiang Province Y202147824Hangzhou City "115" plan to introduce overseas intelligence projects 20220597 and 20210120Medical Health Science and Technology Project of Zhejiang Provincial Health Commission 2023KY210Ministry of Science and Technology of China High-end foreign experts program, G2021017004 and G2022017007LScience and Technology Department of Zhejiang Province 2023ZY1014
6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) is a significant viral pathogen that causes respiratory infections in infants, the elderly, and immunocompromised individuals. RSV-related illnesses impose a substantial economic burden worldwide annually. The molecular structure, function, and in vivo interaction mechanisms of RSV have received more comprehensive attention in recent times, and significant progress has been made in developing inhibitors targeting various stages of the RSV replication cycle. These include fusion inhibitors, RSV polymerase inhibitors, and nucleoprotein inhibitors, as well as FDA-approved RSV prophylactic drugs palivizumab and nirsevimab. The research community is hopeful that these developments might provide easier access to knowledge and might spark new ideas for research programs.

Indexed as

Respiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAgedAnti-Retroviral AgentsAntiviral AgentsHumansInfantPalivizumabAnti-Retroviral AgentsAntiviral AgentsPalivizumabmolecule inhibitormonoclonal antibodiesrespiratory syncytial virus (RSV)vaccine

Identifiers

PMID38338343
PMCPMC10856762
OpenAlexW4391263504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.