Evidence map›Paper›PMID 38337758›Full record

ReviewDiagnostics (Basel, Switzerland)2024

Cerebrospinal Fluid Analysis in Rheumatological Diseases with Neuropsychiatric Complications and Manifestations: A Narrative Review.

Massimiliano Castellazzi, Raffaella Candeloro, Maura Pugliatti, Marcello Govoni, Ettore Silvagni, Alessandra Bortoluzzi

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Guillain-Barré syndrome followingFrontiers in immunology · 2026
    Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Massimiliano CastellazziDepartment of Neurosciences and Rehabilitation, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-6555-6075
Raffaella CandeloroDepartment of Neurosciences and Rehabilitation, University of Ferrara, 44121 Ferrara, Italy.
Maura PugliattiDepartment of Neurosciences and Rehabilitation, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-9396-8683
Marcello GovoniDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-0499-5773
Ettore SilvagniDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Alessandra BortoluzziDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
University of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The analysis of cerebrospinal fluid (CSF) remains a valuable diagnostic tool in the evaluation of inflammatory and infectious conditions involving the brain, spinal cord, and meninges. Since many rheumatic inflammatory diseases can involve the central and peripheral nervous system, the aims of this narrative review were to summarize the latest evidence on the use of CSF analysis in the field of neuropsychiatric manifestations of rheumatic diseases. Routine CSF parameters were taken into consideration for this review: appearance; total protein and cellular content (pleocytosis); lactate and/or glucose; CSF/serum albumin quotient; intrathecal synthesis of IgG. Data regarding the role of CSF analysis in the clinical management of neuropsychiatric systemic lupus erythematosus, primary Sjogren's syndrome, rheumatoid arthritis, and Behçet's syndrome are presented. Although no disease-specific picture has been identified, CSF analysis remains a useful diagnostic tool to confirm the presence of a neuro-inflammatory state or, conversely, to exclude the concomitant presence of other inflammatory/infectious diseases affecting the CNS in the context of systemic rheumatologic conditions.

Indexed as

cerebrospinal fluidneuropsychiatric complicationsrheumatological diseases

Identifiers

PMID38337758
PMCPMC10854855
OpenAlexW4391174659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.