ArticleDiagnostics (Basel, Switzerland)2024
Comparison of Fine-Needle Aspiration Cytopathology with Histopathological Examination of the Thyroid Gland in Patients Undergoing Elective Thyroid Surgery: Do We Still Need Fine-Needle Aspiration Cytopathology?
Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- The impact of a simple positioning aid device on the diagnostic performance of thyroid cancer in CT scans: a randomized controlled trial.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Trial
- Critical assessment of the comparison of needle gauges for fine needle aspiration of lymph nodes and thyroid.Annals of medicine and surgery (2012) · 2026Article
- Beyond Size: Integrating Ultrasonographic Features and FNAB Cytology to Predict Thyroid Malignancy-A Retrospective, Single-Center Study.Journal of clinical medicine · 2026Article
- Predictive Value of Arterial Enhancement Fraction Derived from Dual-Layer Spectral Computed Tomography for Thyroid Microcarcinoma.Diagnostics (Basel, Switzerland) · 2025Article
- Exploring the role of EBV ZEBRA antibody levels in papillary thyroid cancer risk and drug resistance.Discover oncology · 2025Article
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Authors and funding
7 authors.
Funding
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Abstract
backgroundThe thyroid gland is responsible for various functions, but it is susceptible to pathologies. The gold standard for preliminarily diagnosing thyroid abnormalities is fine-needle aspiration cytology (FNAC), although it has some limitations; thus, postoperative histopathological examination confirms the diagnosis. The aim of the present study was to compare preoperative FNAC results with postoperative histopathological examination.
methodsThis study is a retrospective study based on FNAC and postoperative histopathology examination, which were compared and analyzed.
resultsThis study included 344 patients between 18 and 86 years old (mean age: 53.06 ± 13.89), comprising 274 females and 70 males (mean ages 52.72 ± 13.86 and 54.39 ± 14.05, respectively) with a 3.9:1 female-to-male ratio. Statistical significance between the FNAC and histopathology results was observed (
conclusionsDue to many factors, FNAC may lead to over- or under-diagnosis, increasing the chances of complications associated with the selected treatment. However, we do not have any other more accurate tools; therefore, FNAC should still remain as the gold standard of preliminary examination.
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