ReviewJournal of clinical medicine2024
Critical Care Management of Severe Asthma Exacerbations.
Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06652542 (Asthma Exacerbations & Respiratory Management), which is not on this map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Asthma Exacerbations & Respiratory Management: An International Online Survey Endorsed by the International Association of Non-invasive Ventilation & International College of Experts
Who cites it
20 citing papers in PubMed, 29 citations in OpenAlex.
- Heliox ventilation promotes pulmonary circulation and cardiac function in elderly hypertensive patients: a randomized controlled trial.Medical gas research · 2026Trial
- Lactate to albumin ratio LAR predicts mortality in critically ill adults with asthma across two cohorts.Scientific reports · 2026Article
- Review
- Continuous versus intermittent nebulization of salbutamol in acute Severe asthma in children under 12 years of age.Pakistan journal of medical sciences · 2026Article
- Severe hypocapnia-induced coma in an asthma patient: When oxygen therapy becomes a double-edged sword.Qatar medical journal · 2026Article
- Exacerbation of Asthma Among Pediatric Patients Presenting to the Emergency Department.Journal of clinical medicine · 2025Review
- Article
- Effectiveness of Intravenous and Nebulized MgSOChildren (Basel, Switzerland) · 2025Review
- Insights and considerations in the use of biologics for managing eosinophilic exacerbations in asthma and chronic obstructive pulmonary disease.Journal of thoracic disease · 2025Article
- Article
- Status asthmaticus and the use of ketamine nebulization and magnesium sulfate: current strategies and outcomes.Annals of medicine and surgery (2012) · 2025Review
- Electrical impedance tomography-based temporal signals correlate with quantitative computed tomography-based spatial variables in asthma subjects: a pilot study.Frontiers in physiology · 2025Article
- Compassionate use of tezepelumab in near fatal asthma: A case report and review of the literature.Respiratory medicine case reports · 2025Article
- Successful Non-Invasive Management of Near-Fatal Asthma with Severe Hypercapnic Respiratory Failure: A Case Report.International medical case reports journal · 2025Article
- A fluorescent probe for monitoring carboxylesterases in pulmonary cells under permissive hypercapnia condition.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024Article
- Status Asthmaticus in the Pediatric ICU: A Comprehensive Review of Management and Challenges.Pediatric reports · 2024Review
- Peritoneal Infusion of Oxygen Microbubbles Alters the Metabolomic Profile of the Lung and Spleen in Acute Hypoxic Exposure.Bioengineering (Basel, Switzerland) · 2024Article
- Ketamine as an Adjunct Therapy in Acute Severe Asthma: An In-Depth Review of Efficacy and Clinical Implications.Cureus · 2024Review
- Role of Complement Components in Asthma: A Systematic Review.Journal of clinical medicine · 2024Review
- Efficacy of β-agonists in prevention and treatment of acute lung injury: A meta-analysis of randomized controlled trials.Annals of thoracic medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe asthma exacerbations, including near-fatal asthma (NFA), have high morbidity and mortality. Mechanical ventilation of patients with severe asthma is difficult due to the complex pathophysiology resulting from severe bronchospasm and dynamic hyperinflation. Life-threatening complications of traditional ventilation strategies in asthma exacerbations include the development of systemic hypotension from hyperinflation, air trapping, and pneumothoraces. Optimizing pharmacologic techniques and ventilation strategies is crucial to treat the underlying bronchospasm. Despite optimal pharmacologic management and mechanical ventilation, the mortality rate of patients with severe asthma in intensive care units is 8%, suggesting a need for advanced non-pharmacologic therapies, including extracorporeal life support (ECLS). This review focuses on the pathophysiology of acute asthma exacerbations, ventilation management including non-invasive ventilation (NIV) and invasive mechanical ventilation (IMV), the pharmacologic management of acute asthma, and ECLS. This review also explores additional advanced non-pharmacologic techniques and monitoring tools for the safe and effective management of critically ill adult asthmatic patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.